Aquaporins in the hepatobiliary system

Anatoliy I. Masyuk, Nicholas F La Russo

Research output: Contribution to journalArticle

57 Citations (Scopus)

Abstract

The review focuses on the potential physiological and pathophysiological roles of aquaporins (AQPs), a family of water channel proteins, in the hepatobiliary system. Among 13 aquaporins (AQP0-AQP12) cloned in mammals, seven AQPs have been identified in the liver and biliary tree. Accumulating evidence suggests that AQPs are likely involved in canalicular and ductal bile secretion, gluconeogenesis and microbial infection and may have other novel roles that affect liver function.

Original languageEnglish (US)
JournalHepatology
Volume43
Issue number2 SUPPL. 1
DOIs
StatePublished - Feb 2006

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Aquaporins
Gluconeogenesis
Liver
Biliary Tract
Bile
Mammals
Infection

ASJC Scopus subject areas

  • Hepatology

Cite this

Aquaporins in the hepatobiliary system. / Masyuk, Anatoliy I.; La Russo, Nicholas F.

In: Hepatology, Vol. 43, No. 2 SUPPL. 1, 02.2006.

Research output: Contribution to journalArticle

Masyuk, Anatoliy I. ; La Russo, Nicholas F. / Aquaporins in the hepatobiliary system. In: Hepatology. 2006 ; Vol. 43, No. 2 SUPPL. 1.
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