Aquaporins in the hepatobiliary system

Anatoliy I. Masyuk; Nicholas F. LaRusso

doi:10.1002/hep.20996

Aquaporins in the hepatobiliary system

Anatoliy I. Masyuk, Nicholas F. LaRusso

Gastroenterology and Hepatology

Research output: Contribution to journal › Review article › peer-review

62 Scopus citations

Abstract

The review focuses on the potential physiological and pathophysiological roles of aquaporins (AQPs), a family of water channel proteins, in the hepatobiliary system. Among 13 aquaporins (AQP0-AQP12) cloned in mammals, seven AQPs have been identified in the liver and biliary tree. Accumulating evidence suggests that AQPs are likely involved in canalicular and ductal bile secretion, gluconeogenesis and microbial infection and may have other novel roles that affect liver function.

Original language	English (US)
Pages (from-to)	S75-S81
Journal	Hepatology
Volume	43
Issue number	2 SUPPL. 1
DOIs	https://doi.org/10.1002/hep.20996
State	Published - Feb 2006

ASJC Scopus subject areas

Hepatology

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10.1002/hep.20996

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AB - The review focuses on the potential physiological and pathophysiological roles of aquaporins (AQPs), a family of water channel proteins, in the hepatobiliary system. Among 13 aquaporins (AQP0-AQP12) cloned in mammals, seven AQPs have been identified in the liver and biliary tree. Accumulating evidence suggests that AQPs are likely involved in canalicular and ductal bile secretion, gluconeogenesis and microbial infection and may have other novel roles that affect liver function.

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Aquaporins in the hepatobiliary system

Abstract

ASJC Scopus subject areas

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