Applied nanotechnology and nanoscience in orthopedic oncology

Olga D. Savvidou, Ioanna K. Bolia, George D. Chloros, Stavros D. Goumenos, Vasileios I. Sakellariou, Evanthia Galanis, Panayiotis J. Papagelopoulos

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Nanomedicine is based on the fact that biological molecules behave similarly to nanomolecules, which have a size of less than 100 nm, and is now affecting most areas of orthopedics. In orthopedic oncology, most of the in vitro and in vivo studies have used osteosarcoma or Ewing sarcoma cell lineages. In this article, tumor imaging and treatment nanotechnology applications, including nanostructure delivery of chemotherapeutic agents, gene therapy, and the role of nano-selenium-coated implants, are outlined. Finally, the potential role of nanotechnology in addressing the challenges of drug and radiotherapy resistance is discussed.

Original languageEnglish (US)
Pages (from-to)280-286
Number of pages7
JournalOrthopedics
Volume39
Issue number5
DOIs
StatePublished - Sep 1 2016

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

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  • Cite this

    Savvidou, O. D., Bolia, I. K., Chloros, G. D., Goumenos, S. D., Sakellariou, V. I., Galanis, E., & Papagelopoulos, P. J. (2016). Applied nanotechnology and nanoscience in orthopedic oncology. Orthopedics, 39(5), 280-286. https://doi.org/10.3928/01477447-20160823-03