Applied nanotechnology and nanoscience in orthopedic oncology

Olga D. Savvidou, Ioanna K. Bolia, George D. Chloros, Stavros D. Goumenos, Vasileios I. Sakellariou, Evanthia Galanis, Panayiotis J. Papagelopoulos

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Nanomedicine is based on the fact that biological molecules behave similarly to nanomolecules, which have a size of less than 100 nm, and is now affecting most areas of orthopedics. In orthopedic oncology, most of the in vitro and in vivo studies have used osteosarcoma or Ewing sarcoma cell lineages. In this article, tumor imaging and treatment nanotechnology applications, including nanostructure delivery of chemotherapeutic agents, gene therapy, and the role of nano-selenium-coated implants, are outlined. Finally, the potential role of nanotechnology in addressing the challenges of drug and radiotherapy resistance is discussed.

Original languageEnglish (US)
Pages (from-to)280-286
Number of pages7
JournalOrthopedics
Volume39
Issue number5
DOIs
StatePublished - Sep 1 2016

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Nanotechnology
Orthopedics
Nanomedicine
Ewing's Sarcoma
Nanostructures
Cell Lineage
Osteosarcoma
Selenium
Drug Resistance
Genetic Therapy
Radiotherapy
Neoplasms
Therapeutics
In Vitro Techniques

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Savvidou, O. D., Bolia, I. K., Chloros, G. D., Goumenos, S. D., Sakellariou, V. I., Galanis, E., & Papagelopoulos, P. J. (2016). Applied nanotechnology and nanoscience in orthopedic oncology. Orthopedics, 39(5), 280-286. https://doi.org/10.3928/01477447-20160823-03

Applied nanotechnology and nanoscience in orthopedic oncology. / Savvidou, Olga D.; Bolia, Ioanna K.; Chloros, George D.; Goumenos, Stavros D.; Sakellariou, Vasileios I.; Galanis, Evanthia; Papagelopoulos, Panayiotis J.

In: Orthopedics, Vol. 39, No. 5, 01.09.2016, p. 280-286.

Research output: Contribution to journalArticle

Savvidou, OD, Bolia, IK, Chloros, GD, Goumenos, SD, Sakellariou, VI, Galanis, E & Papagelopoulos, PJ 2016, 'Applied nanotechnology and nanoscience in orthopedic oncology', Orthopedics, vol. 39, no. 5, pp. 280-286. https://doi.org/10.3928/01477447-20160823-03
Savvidou OD, Bolia IK, Chloros GD, Goumenos SD, Sakellariou VI, Galanis E et al. Applied nanotechnology and nanoscience in orthopedic oncology. Orthopedics. 2016 Sep 1;39(5):280-286. https://doi.org/10.3928/01477447-20160823-03
Savvidou, Olga D. ; Bolia, Ioanna K. ; Chloros, George D. ; Goumenos, Stavros D. ; Sakellariou, Vasileios I. ; Galanis, Evanthia ; Papagelopoulos, Panayiotis J. / Applied nanotechnology and nanoscience in orthopedic oncology. In: Orthopedics. 2016 ; Vol. 39, No. 5. pp. 280-286.
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