Applications of Cardiac Computed Tomography in the Cardio-Oncology Population

Michael E. Layoun, Eric H. Yang, Joerg Herrmann, Cezar A. Iliescu, Juan C. Lopez-Mattei, Kostas Marmagkiolis, Matthew J. Budoff, Maros Ferencik

Research output: Contribution to journalReview article

2 Scopus citations

Abstract

The increased risk for cardiovascular events in aging cancer survivors and those undergoing certain chemotherapeutic treatments has raised concern for more rigorous screening and surveillance methods above that of the general population. At this time, there are limited guidelines for how to best manage this vulnerable cohort. Questions regarding timing of screening, choice of imaging modality and risk reduction strategies—especially in those patients with known atherosclerotic disease—remain to be elucidated. Over a decade of case series, retrospective studies and clinical trials have shed light on the evolving role of cardiac computed tomography (CT) in this population, of which there is a relative paucity of data regarding its potential utility in the specific cardio-oncology population. Focusing on ability of cardiac CT to evaluate multiple cardiac and vascular structures, provide diagnostic and prognostic information, as well as assist interventional and surgical colleagues in surgical/percutaneous valve replacement and revascularization strategies is the premise for this review.

Original languageEnglish (US)
Article number47
JournalCurrent treatment options in oncology
Volume20
Issue number6
DOIs
StatePublished - Jun 1 2019

Keywords

  • Cardiac computed tomography angiography
  • Cardiotoxicity
  • Coronary artery calcium score
  • Radiation-induced valvulopathy
  • Vasculotoxicity

ASJC Scopus subject areas

  • Oncology
  • Pharmacology (medical)

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    Layoun, M. E., Yang, E. H., Herrmann, J., Iliescu, C. A., Lopez-Mattei, J. C., Marmagkiolis, K., Budoff, M. J., & Ferencik, M. (2019). Applications of Cardiac Computed Tomography in the Cardio-Oncology Population. Current treatment options in oncology, 20(6), [47]. https://doi.org/10.1007/s11864-019-0645-2