Aortic reconstruction in kidney transplant recipients

Jean M. Panneton, Peter Gloviczki, Linda G. Canton, Thomas C. Bower, Matthew S T Chow, Peter C. Pairolero, Hartzell V Schaff, John W. Hallett, Kenneth J. Cherry

Research output: Contribution to journalArticle

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Abstract

Renal transplantation has increased the longevity of patients with uremia. An increasing number undergo aortic reconstruction, which exposes the transplanted kidney to ischemic injury. To evaluate the risk for renal failure, loss of the transplant, and methods of renal protection, we reviewed our experience. Clinical data were reviewed for 10 consecutive patients (7 men, 3 women; mean age 52.7 years [range 32 to 75 years]) with a transplanted kidney who underwent aortic reconstruction between 1977 and 1994 at our institution. Mean interval between renal transplantation and aortic reconstruction was 5.9 years (range 1 month to 12.7 years). Seven patients required emergency repair because of dissection (2 patients), aneurysm rupture (4 patients), or symptomatic aneurysm (1 patient); three underwent elective repair. Reasons for reconstruction included aortic dissection (2 patients), aneurysm of the descending thoracic (2 patients), thoracoabdominal (1 patient), or abdominal aorta (3 patients), and aortoiliac occlusive disease (2 patients). Patients with thoracic or thoracoabdominal reconstructions underwent repair with atriofemoral, aortofemoral, or femorofemoral shunt placement or bypass. Of the five abdominal aortic reconstructions, the kidney was protected with aortofemoral shunt placement in one patient and cold renal perfusion in three. In two of them, topical cooling of the kidney also was used. One patient with acute aortic dissection died at 39 days as a result of respiratory failure. Loss of the recently transplanted kidney was caused by acute rejection. One patient had a transient increase in serum creatinine concentration. Eight had no worsening of renal function, and none of the nine survivors lost the transplanted kidney. We conclude that aortic reconstruction can be safely performed in kidney transplant recipients. Patients in whom thoracic or thoracoabdominal aortic reconstruction was required were protected with an atriofemoral or aortofemoral bypass or shunt. Patients undergoing abdominal aortic reconstruction did well when cold renal perfusion with or without local cooling of the transplant was used for renal protection. Transplanted kidneys appeared to tolerate ischemic injury similarly to native kidneys.

Original languageEnglish (US)
Pages (from-to)97-108
Number of pages12
JournalAnnals of Vascular Surgery
Volume10
Issue number2
DOIs
StatePublished - Mar 1996

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Kidney
Aneurysm
Dissection
Transplant Recipients
Thorax
Kidney Transplantation
Perfusion
Transplants
Uremia
Abdominal Aorta
Wounds and Injuries
Respiratory Insufficiency
Renal Insufficiency
Survivors
Rupture
Creatinine
Emergencies

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Panneton, J. M., Gloviczki, P., Canton, L. G., Bower, T. C., Chow, M. S. T., Pairolero, P. C., ... Cherry, K. J. (1996). Aortic reconstruction in kidney transplant recipients. Annals of Vascular Surgery, 10(2), 97-108. https://doi.org/10.1007/BF02000752

Aortic reconstruction in kidney transplant recipients. / Panneton, Jean M.; Gloviczki, Peter; Canton, Linda G.; Bower, Thomas C.; Chow, Matthew S T; Pairolero, Peter C.; Schaff, Hartzell V; Hallett, John W.; Cherry, Kenneth J.

In: Annals of Vascular Surgery, Vol. 10, No. 2, 03.1996, p. 97-108.

Research output: Contribution to journalArticle

Panneton, JM, Gloviczki, P, Canton, LG, Bower, TC, Chow, MST, Pairolero, PC, Schaff, HV, Hallett, JW & Cherry, KJ 1996, 'Aortic reconstruction in kidney transplant recipients', Annals of Vascular Surgery, vol. 10, no. 2, pp. 97-108. https://doi.org/10.1007/BF02000752
Panneton JM, Gloviczki P, Canton LG, Bower TC, Chow MST, Pairolero PC et al. Aortic reconstruction in kidney transplant recipients. Annals of Vascular Surgery. 1996 Mar;10(2):97-108. https://doi.org/10.1007/BF02000752
Panneton, Jean M. ; Gloviczki, Peter ; Canton, Linda G. ; Bower, Thomas C. ; Chow, Matthew S T ; Pairolero, Peter C. ; Schaff, Hartzell V ; Hallett, John W. ; Cherry, Kenneth J. / Aortic reconstruction in kidney transplant recipients. In: Annals of Vascular Surgery. 1996 ; Vol. 10, No. 2. pp. 97-108.
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