Aortic dilatation and calcification in asymptomatic patients with bicuspid aortic valve: Analysis in a Korean health screening population

Mirae Lee, Jidong Sung, Soo Jin Cho, Soo Hee Choi, Sung Won Cho, Jae Kuen Oh, Sung Ji Park, Duk Kyung Kim

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Entire anatomic area involved in the bicuspid aortic valve (BAV) disease has not been studied well, especially in Asian populations. We investigated prevalence and vascular characteristics of the BAV disease in a Korean population. In a health screening program from 2005 through 2010, 38 BAV patients (BAV group, 0.16 %, 35 males) were isolated among a total of 23,291 persons based on echocardiography. Each BAV patient was matched with three TAV patients (TAV group, n = 114) of the same age, gender, BSA, and hypertension. Using echocardiography and low-dose chest CT scan, diameters of the aortic root to proximal descending aorta (pDA) and pulmonary artery (PA), morphologic types of BAV, and calcification in the aortic root were evaluated in both groups. Diameters of the sinotubular junction and ascending aorta in BAV group were larger than in TAV group (29 ± 7 vs. 27 ± 3 mm, p = 0.046; 42 ± 7 vs. 34 ± 4 mm, p < 0.001, respectively). Diameters of the annulus, sinus of Valsalva, aortic arch, pDA, and PA were not different between two groups. Calcification in the aortic root was approximately seven times more common in BAV group (p < 0.001). Diameters of the aortic root were larger in the R-L type (n = 24) than in the R-N type (n = 11). Prevalence of BAV in a Korean population appears lower than in Western populations. Within the entire anatomic boundaries of BAV, the ascending aorta was predominantly dilated in BAV patients. The R-L type showed more dilatation than the R-N type, not in the ascending aorta but in the aortic root.

Original languageEnglish (US)
Pages (from-to)553-560
Number of pages8
JournalInternational Journal of Cardiovascular Imaging
Volume29
Issue number3
DOIs
StatePublished - Mar 2013

Fingerprint

Dilatation
Health
Population
Thoracic Aorta
Aorta
Aortic Diseases
Pulmonary Artery
Echocardiography
Bicuspid Aortic Valve
Sinus of Valsalva
Blood Vessels
Thorax
Hypertension

Keywords

  • Aortic calcification
  • Aortic dilatation
  • Bicuspid aortic valve
  • Koreans

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Aortic dilatation and calcification in asymptomatic patients with bicuspid aortic valve : Analysis in a Korean health screening population. / Lee, Mirae; Sung, Jidong; Cho, Soo Jin; Choi, Soo Hee; Cho, Sung Won; Oh, Jae Kuen; Park, Sung Ji; Kim, Duk Kyung.

In: International Journal of Cardiovascular Imaging, Vol. 29, No. 3, 03.2013, p. 553-560.

Research output: Contribution to journalArticle

Lee, Mirae ; Sung, Jidong ; Cho, Soo Jin ; Choi, Soo Hee ; Cho, Sung Won ; Oh, Jae Kuen ; Park, Sung Ji ; Kim, Duk Kyung. / Aortic dilatation and calcification in asymptomatic patients with bicuspid aortic valve : Analysis in a Korean health screening population. In: International Journal of Cardiovascular Imaging. 2013 ; Vol. 29, No. 3. pp. 553-560.
@article{c75cf1d102744ec7afe6d4a125ac9cef,
title = "Aortic dilatation and calcification in asymptomatic patients with bicuspid aortic valve: Analysis in a Korean health screening population",
abstract = "Entire anatomic area involved in the bicuspid aortic valve (BAV) disease has not been studied well, especially in Asian populations. We investigated prevalence and vascular characteristics of the BAV disease in a Korean population. In a health screening program from 2005 through 2010, 38 BAV patients (BAV group, 0.16 {\%}, 35 males) were isolated among a total of 23,291 persons based on echocardiography. Each BAV patient was matched with three TAV patients (TAV group, n = 114) of the same age, gender, BSA, and hypertension. Using echocardiography and low-dose chest CT scan, diameters of the aortic root to proximal descending aorta (pDA) and pulmonary artery (PA), morphologic types of BAV, and calcification in the aortic root were evaluated in both groups. Diameters of the sinotubular junction and ascending aorta in BAV group were larger than in TAV group (29 ± 7 vs. 27 ± 3 mm, p = 0.046; 42 ± 7 vs. 34 ± 4 mm, p < 0.001, respectively). Diameters of the annulus, sinus of Valsalva, aortic arch, pDA, and PA were not different between two groups. Calcification in the aortic root was approximately seven times more common in BAV group (p < 0.001). Diameters of the aortic root were larger in the R-L type (n = 24) than in the R-N type (n = 11). Prevalence of BAV in a Korean population appears lower than in Western populations. Within the entire anatomic boundaries of BAV, the ascending aorta was predominantly dilated in BAV patients. The R-L type showed more dilatation than the R-N type, not in the ascending aorta but in the aortic root.",
keywords = "Aortic calcification, Aortic dilatation, Bicuspid aortic valve, Koreans",
author = "Mirae Lee and Jidong Sung and Cho, {Soo Jin} and Choi, {Soo Hee} and Cho, {Sung Won} and Oh, {Jae Kuen} and Park, {Sung Ji} and Kim, {Duk Kyung}",
year = "2013",
month = "3",
doi = "10.1007/s10554-012-0116-3",
language = "English (US)",
volume = "29",
pages = "553--560",
journal = "International Journal of Cardiovascular Imaging",
issn = "1569-5794",
publisher = "Springer Netherlands",
number = "3",

}

TY - JOUR

T1 - Aortic dilatation and calcification in asymptomatic patients with bicuspid aortic valve

T2 - Analysis in a Korean health screening population

AU - Lee, Mirae

AU - Sung, Jidong

AU - Cho, Soo Jin

AU - Choi, Soo Hee

AU - Cho, Sung Won

AU - Oh, Jae Kuen

AU - Park, Sung Ji

AU - Kim, Duk Kyung

PY - 2013/3

Y1 - 2013/3

N2 - Entire anatomic area involved in the bicuspid aortic valve (BAV) disease has not been studied well, especially in Asian populations. We investigated prevalence and vascular characteristics of the BAV disease in a Korean population. In a health screening program from 2005 through 2010, 38 BAV patients (BAV group, 0.16 %, 35 males) were isolated among a total of 23,291 persons based on echocardiography. Each BAV patient was matched with three TAV patients (TAV group, n = 114) of the same age, gender, BSA, and hypertension. Using echocardiography and low-dose chest CT scan, diameters of the aortic root to proximal descending aorta (pDA) and pulmonary artery (PA), morphologic types of BAV, and calcification in the aortic root were evaluated in both groups. Diameters of the sinotubular junction and ascending aorta in BAV group were larger than in TAV group (29 ± 7 vs. 27 ± 3 mm, p = 0.046; 42 ± 7 vs. 34 ± 4 mm, p < 0.001, respectively). Diameters of the annulus, sinus of Valsalva, aortic arch, pDA, and PA were not different between two groups. Calcification in the aortic root was approximately seven times more common in BAV group (p < 0.001). Diameters of the aortic root were larger in the R-L type (n = 24) than in the R-N type (n = 11). Prevalence of BAV in a Korean population appears lower than in Western populations. Within the entire anatomic boundaries of BAV, the ascending aorta was predominantly dilated in BAV patients. The R-L type showed more dilatation than the R-N type, not in the ascending aorta but in the aortic root.

AB - Entire anatomic area involved in the bicuspid aortic valve (BAV) disease has not been studied well, especially in Asian populations. We investigated prevalence and vascular characteristics of the BAV disease in a Korean population. In a health screening program from 2005 through 2010, 38 BAV patients (BAV group, 0.16 %, 35 males) were isolated among a total of 23,291 persons based on echocardiography. Each BAV patient was matched with three TAV patients (TAV group, n = 114) of the same age, gender, BSA, and hypertension. Using echocardiography and low-dose chest CT scan, diameters of the aortic root to proximal descending aorta (pDA) and pulmonary artery (PA), morphologic types of BAV, and calcification in the aortic root were evaluated in both groups. Diameters of the sinotubular junction and ascending aorta in BAV group were larger than in TAV group (29 ± 7 vs. 27 ± 3 mm, p = 0.046; 42 ± 7 vs. 34 ± 4 mm, p < 0.001, respectively). Diameters of the annulus, sinus of Valsalva, aortic arch, pDA, and PA were not different between two groups. Calcification in the aortic root was approximately seven times more common in BAV group (p < 0.001). Diameters of the aortic root were larger in the R-L type (n = 24) than in the R-N type (n = 11). Prevalence of BAV in a Korean population appears lower than in Western populations. Within the entire anatomic boundaries of BAV, the ascending aorta was predominantly dilated in BAV patients. The R-L type showed more dilatation than the R-N type, not in the ascending aorta but in the aortic root.

KW - Aortic calcification

KW - Aortic dilatation

KW - Bicuspid aortic valve

KW - Koreans

UR - http://www.scopus.com/inward/record.url?scp=84879554171&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879554171&partnerID=8YFLogxK

U2 - 10.1007/s10554-012-0116-3

DO - 10.1007/s10554-012-0116-3

M3 - Article

C2 - 22923281

AN - SCOPUS:84879554171

VL - 29

SP - 553

EP - 560

JO - International Journal of Cardiovascular Imaging

JF - International Journal of Cardiovascular Imaging

SN - 1569-5794

IS - 3

ER -