Antinuclear Antibody Staining Only Centrioles in a Patient with Scleroderma

Thomas Osborn, Nirupa J. Patel, Stephen C. Ross, Nancy E. Bauer

Research output: Contribution to journalLetter

12 Citations (Scopus)

Abstract

To the Editor: In their letter in the September 17 issue McCarty et al. reported a pattern of staining localized to the mitotic-spindle apparatus.1 We would like to report the observation of a unique anticentriolar antibody present in a patient with progressive systemic sclerosis. The patient had sclerodactyly, proximal edematous skin changes, and Raynaud's phenomenon. She did not have the carpal-tunnel syndrome, which was a prominent feature in the patients described by McCarty et al. She was not taking alkaloids or colchicine. Her serum cortisol level was normal, and there was no serologic evidence of infectious mononucleosis. The fluorescence staining.

Original languageEnglish (US)
Pages (from-to)253-254
Number of pages2
JournalNew England Journal of Medicine
Volume307
Issue number4
DOIs
StatePublished - Jul 22 1982
Externally publishedYes

Fingerprint

Centrioles
Antinuclear Antibodies
Staining and Labeling
Diffuse Scleroderma
Infectious Mononucleosis
Raynaud Disease
Spindle Apparatus
Carpal Tunnel Syndrome
Colchicine
Alkaloids
Hydrocortisone
Fluorescence
Observation
Skin
Antibodies
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Antinuclear Antibody Staining Only Centrioles in a Patient with Scleroderma. / Osborn, Thomas; Patel, Nirupa J.; Ross, Stephen C.; Bauer, Nancy E.

In: New England Journal of Medicine, Vol. 307, No. 4, 22.07.1982, p. 253-254.

Research output: Contribution to journalLetter

Osborn, Thomas ; Patel, Nirupa J. ; Ross, Stephen C. ; Bauer, Nancy E. / Antinuclear Antibody Staining Only Centrioles in a Patient with Scleroderma. In: New England Journal of Medicine. 1982 ; Vol. 307, No. 4. pp. 253-254.
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