Antimicrobial activity of metabolites from soft corals of Indian ocean

P. Radhika, C. Subrahmanyam, P. Ellaiah, K. Adinarayana

Research output: Contribution to journalArticlepeer-review

Abstract

Eight secondary metabolite compounds A to H, namely a sphingosine glycoside (A), a sphingosine (B), two lipid glycosides (C & D), two sterols (E & G) and two sterol glycosides (F & H), obtained from some soft corals of the Indian coast, were tested for their antibacterial and antifungal activity at different concentrations. Compounds B-E showed significant antibacterial activity at 200 μg mL-1 concentration. Compounds A and G showed the same antifungal activity as ketoconazole against Rhizopus oryzae at 200 μg mL-1, while compounds B and D were significantly active against Aspergillus niger at 200 μg mL-1.

Keywords

  • Antibacterial
  • Antifungal
  • Cladiella
  • Lobophytum
  • Sinularia
  • Soft corals
  • Sphingolipids
  • Sterols

ASJC Scopus subject areas

  • Microbiology

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