Antimicrobial activity of metabolites from soft corals of Indian ocean

Eight secondary metabolite compounds A to H, namely a sphingosine glycoside (A), a sphingosine (B), two lipid glycosides (C & D), two sterols (E & G) and two sterol glycosides (F & H), obtained from some soft corals of the Indian coast, were tested for their antibacterial and antifungal activity at different concentrations. Compounds B-E showed significant antibacterial activity at 200 μg mL^-1 concentration. Compounds A and G showed the same antifungal activity as ketoconazole against Rhizopus oryzae at 200 μg mL^-1, while compounds B and D were significantly active against Aspergillus niger at 200 μg mL^-1.