Antibody-mediated rejection in liver transplantation: Current controversies and future directions

Timucin Taner; Mark D. Stegall; Julie K. Heimbach

doi:10.1002/lt.23826

Antibody-mediated rejection in liver transplantation: Current controversies and future directions

Timucin Taner, Mark D. Stegall, Julie K. Heimbach

Transplant Surgery

Research output: Contribution to journal › Review article › peer-review

40 Scopus citations

Abstract

Interest in the role of donor-specific human leukocyte antibodies in liver transplantation has been rekindled recently. Emerging evidence suggests that these antibodies may cause injury to the liver allograft. Here we review the clinical literature, highlight controversial results, and propose a path forward for the definition and better understanding of antibody-mediated injury to the liver.

Original language	English (US)
Pages (from-to)	514-527
Number of pages	14
Journal	Liver Transplantation
Volume	20
Issue number	5
DOIs	https://doi.org/10.1002/lt.23826
State	Published - May 2014

ASJC Scopus subject areas

Surgery
Hepatology
Transplantation

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10.1002/lt.23826

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abstract = "Interest in the role of donor-specific human leukocyte antibodies in liver transplantation has been rekindled recently. Emerging evidence suggests that these antibodies may cause injury to the liver allograft. Here we review the clinical literature, highlight controversial results, and propose a path forward for the definition and better understanding of antibody-mediated injury to the liver.",

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AB - Interest in the role of donor-specific human leukocyte antibodies in liver transplantation has been rekindled recently. Emerging evidence suggests that these antibodies may cause injury to the liver allograft. Here we review the clinical literature, highlight controversial results, and propose a path forward for the definition and better understanding of antibody-mediated injury to the liver.

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Antibody-mediated rejection in liver transplantation: Current controversies and future directions

Abstract

ASJC Scopus subject areas

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