Abstract
While many advances have occurred in the nonpharmacologic treatment of ventricular arrhythmias, antiarrhythmic medications remain indispensable in the acute treatment and prevention of recurrent ventricular arrhythmias. Additionally, it is important to understand the effects of medications on neurohormonal modulation and defibrillation thresholds. Some antiarrhythmics have specialized uses for specific arrhythmias, and some can be used in the electrophysiology lab for diagnostic testing and aid during ablations. In contrast, amiodarone is effective for various arrhythmias, but it has many extracardiac toxicities. This chapter discusses the pharmacology and clinical use of antiarrhythmics for diagnostic and therapeutic management of ventricular arrhythmias.
| Original language | English (US) |
|---|---|
| Title of host publication | Pathophysiology and Pharmacotherapy of Cardiovascular Disease |
| Publisher | Springer International Publishing |
| Pages | 1101-1133 |
| Number of pages | 33 |
| ISBN (Electronic) | 9783319159614 |
| ISBN (Print) | 9783319159607 |
| DOIs | |
| State | Published - Jan 1 2015 |
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Keywords
- Amiodarone
- Antiarrhythmic medications
- Cardioversion
- ICD
- Potassium channel blocker
- QT interval
- Sodium channel blocker
- Ventricular arrhythmia
- Ventricular fibrillation
- Ventricular tachycardia
ASJC Scopus subject areas
- Medicine(all)
- Pharmacology, Toxicology and Pharmaceutics(all)
Cite this
Antiarrhythmic drugs and management of ventricular arrhythmias. / Schleifer, J. William; Srivathsan, Komandoor.
Pathophysiology and Pharmacotherapy of Cardiovascular Disease. Springer International Publishing, 2015. p. 1101-1133.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Antiarrhythmic drugs and management of ventricular arrhythmias
AU - Schleifer, J. William
AU - Srivathsan, Komandoor
PY - 2015/1/1
Y1 - 2015/1/1
N2 - While many advances have occurred in the nonpharmacologic treatment of ventricular arrhythmias, antiarrhythmic medications remain indispensable in the acute treatment and prevention of recurrent ventricular arrhythmias. Additionally, it is important to understand the effects of medications on neurohormonal modulation and defibrillation thresholds. Some antiarrhythmics have specialized uses for specific arrhythmias, and some can be used in the electrophysiology lab for diagnostic testing and aid during ablations. In contrast, amiodarone is effective for various arrhythmias, but it has many extracardiac toxicities. This chapter discusses the pharmacology and clinical use of antiarrhythmics for diagnostic and therapeutic management of ventricular arrhythmias.
AB - While many advances have occurred in the nonpharmacologic treatment of ventricular arrhythmias, antiarrhythmic medications remain indispensable in the acute treatment and prevention of recurrent ventricular arrhythmias. Additionally, it is important to understand the effects of medications on neurohormonal modulation and defibrillation thresholds. Some antiarrhythmics have specialized uses for specific arrhythmias, and some can be used in the electrophysiology lab for diagnostic testing and aid during ablations. In contrast, amiodarone is effective for various arrhythmias, but it has many extracardiac toxicities. This chapter discusses the pharmacology and clinical use of antiarrhythmics for diagnostic and therapeutic management of ventricular arrhythmias.
KW - Amiodarone
KW - Antiarrhythmic medications
KW - Cardioversion
KW - ICD
KW - Potassium channel blocker
KW - QT interval
KW - Sodium channel blocker
KW - Ventricular arrhythmia
KW - Ventricular fibrillation
KW - Ventricular tachycardia
UR - http://www.scopus.com/inward/record.url?scp=84944145315&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84944145315&partnerID=8YFLogxK
U2 - 10.1007/978-3-319-15961-4_52
DO - 10.1007/978-3-319-15961-4_52
M3 - Chapter
AN - SCOPUS:84944145315
SN - 9783319159607
SP - 1101
EP - 1133
BT - Pathophysiology and Pharmacotherapy of Cardiovascular Disease
PB - Springer International Publishing
ER -