Abstract
While many advances have occurred in the nonpharmacologic treatment of ventricular arrhythmias, antiarrhythmic medications remain indispensable in the acute treatment and prevention of recurrent ventricular arrhythmias. Additionally, it is important to understand the effects of medications on neurohormonal modulation and defibrillation thresholds. Some antiarrhythmics have specialized uses for specific arrhythmias, and some can be used in the electrophysiology lab for diagnostic testing and aid during ablations. In contrast, amiodarone is effective for various arrhythmias, but it has many extracardiac toxicities. This chapter discusses the pharmacology and clinical use of antiarrhythmics for diagnostic and therapeutic management of ventricular arrhythmias.
| Original language | English (US) |
|---|---|
| Title of host publication | Pathophysiology and Pharmacotherapy of Cardiovascular Disease |
| Publisher | Springer International Publishing |
| Pages | 1101-1133 |
| Number of pages | 33 |
| ISBN (Electronic) | 9783319159614 |
| ISBN (Print) | 9783319159607 |
| DOIs | |
| State | Published - Jan 1 2015 |
Keywords
- Amiodarone
- Antiarrhythmic medications
- Cardioversion
- ICD
- Potassium channel blocker
- QT interval
- Sodium channel blocker
- Ventricular arrhythmia
- Ventricular fibrillation
- Ventricular tachycardia
ASJC Scopus subject areas
- Medicine(all)
- Pharmacology, Toxicology and Pharmaceutics(all)