Antiarrhythmic drugs and management of ventricular arrhythmias

J. William Schleifer; Komandoor Srivathsan

doi:10.1007/978-3-319-15961-4_52

Antiarrhythmic drugs and management of ventricular arrhythmias

J. William Schleifer, Komandoor Srivathsan

Cardiovascular Diseases

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

While many advances have occurred in the nonpharmacologic treatment of ventricular arrhythmias, antiarrhythmic medications remain indispensable in the acute treatment and prevention of recurrent ventricular arrhythmias. Additionally, it is important to understand the effects of medications on neurohormonal modulation and defibrillation thresholds. Some antiarrhythmics have specialized uses for specific arrhythmias, and some can be used in the electrophysiology lab for diagnostic testing and aid during ablations. In contrast, amiodarone is effective for various arrhythmias, but it has many extracardiac toxicities. This chapter discusses the pharmacology and clinical use of antiarrhythmics for diagnostic and therapeutic management of ventricular arrhythmias.

Original language	English (US)
Title of host publication	Pathophysiology and Pharmacotherapy of Cardiovascular Disease
Publisher	Springer International Publishing
Pages	1101-1133
Number of pages	33
ISBN (Electronic)	9783319159614
ISBN (Print)	9783319159607
DOIs	https://doi.org/10.1007/978-3-319-15961-4_52
State	Published - Jan 1 2015

Keywords

Amiodarone
Antiarrhythmic medications
Cardioversion
ICD
Potassium channel blocker
QT interval
Sodium channel blocker
Ventricular arrhythmia
Ventricular fibrillation
Ventricular tachycardia

ASJC Scopus subject areas

Medicine(all)
Pharmacology, Toxicology and Pharmaceutics(all)

Access to Document

10.1007/978-3-319-15961-4_52

Cite this

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abstract = "While many advances have occurred in the nonpharmacologic treatment of ventricular arrhythmias, antiarrhythmic medications remain indispensable in the acute treatment and prevention of recurrent ventricular arrhythmias. Additionally, it is important to understand the effects of medications on neurohormonal modulation and defibrillation thresholds. Some antiarrhythmics have specialized uses for specific arrhythmias, and some can be used in the electrophysiology lab for diagnostic testing and aid during ablations. In contrast, amiodarone is effective for various arrhythmias, but it has many extracardiac toxicities. This chapter discusses the pharmacology and clinical use of antiarrhythmics for diagnostic and therapeutic management of ventricular arrhythmias.",

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AU - Srivathsan, Komandoor

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AB - While many advances have occurred in the nonpharmacologic treatment of ventricular arrhythmias, antiarrhythmic medications remain indispensable in the acute treatment and prevention of recurrent ventricular arrhythmias. Additionally, it is important to understand the effects of medications on neurohormonal modulation and defibrillation thresholds. Some antiarrhythmics have specialized uses for specific arrhythmias, and some can be used in the electrophysiology lab for diagnostic testing and aid during ablations. In contrast, amiodarone is effective for various arrhythmias, but it has many extracardiac toxicities. This chapter discusses the pharmacology and clinical use of antiarrhythmics for diagnostic and therapeutic management of ventricular arrhythmias.

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KW - Antiarrhythmic medications

KW - Cardioversion

KW - ICD

KW - Potassium channel blocker

KW - QT interval

KW - Sodium channel blocker

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KW - Ventricular fibrillation

KW - Ventricular tachycardia

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ER -

Antiarrhythmic drugs and management of ventricular arrhythmias

Abstract

Keywords

ASJC Scopus subject areas

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