Anterior Temporal Lobectomy for the Control of Partial Complex Seizures: Information for Counseling Patients

ROBERT J. IVNIK, FRANK W. SHARBROUGH, EDWARD R. LAWS

Research output: Contribution to journalArticle

78 Scopus citations

Abstract

We examined the effect of anterior temporal lobectomy on cognitive function in the treatment of intractable partial complex seizures in a sample of 142 patients. Our current results replicate previous work in this area and clearly establish the presence of differential effects on cognitive function as a consequence of the side of the operation. Learning and memory are most susceptible to impairment postoperatively, although general intellectual abilities are also affected in a small number of patients. The data are further analyzed in a manner that permits determination of the probability of cognitive alterations postoperatively for individual patients. Information is provided to assist health-care professionals in evaluating the risk-to-benefit ratio relative to cognitive abilities as they consider this treatment alternative for their patients who suffer from intractable partial complex seizures.

Original languageEnglish (US)
Pages (from-to)783-793
Number of pages11
JournalMayo Clinic proceedings
Volume63
Issue number8
DOIs
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Medicine(all)

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