Anomalous serum thyroxin measurements with the Abbott TDx procedure

S. Levine; R. Noth; A. Loo; I. J. Chopra; G. G. Klee

doi:10.1093/clinchem/36.10.1838

Anomalous serum thyroxin measurements with the Abbott TDx procedure

S. Levine, R. Noth, A. Loo, I. J. Chopra, G. G. Klee

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

We describe a patient whose serum gave consistently low results for thyroxin as measured with the Abbott TDx but normal results by radioimmunoassay. Further clinical and laboratory studies did not support the low TDx results. Anti-thyroxin antibodies did not explain the discordant results, and we found no evidence of heterophilic antibodies in the patient's serum. We were unable to identify the cause of the problem.

Original language	English (US)
Pages (from-to)	1838-1840
Number of pages	3
Journal	Clinical chemistry
Volume	36
Issue number	10
DOIs	https://doi.org/10.1093/clinchem/36.10.1838
State	Published - 1990

Keywords

Fluorescence polarization immunoassay
analytical error
radioimmunoassay compared

ASJC Scopus subject areas

Clinical Biochemistry
Biochemistry, medical

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10.1093/clinchem/36.10.1838

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abstract = "We describe a patient whose serum gave consistently low results for thyroxin as measured with the Abbott TDx but normal results by radioimmunoassay. Further clinical and laboratory studies did not support the low TDx results. Anti-thyroxin antibodies did not explain the discordant results, and we found no evidence of heterophilic antibodies in the patient's serum. We were unable to identify the cause of the problem.",

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AU - Loo, A.

AU - Chopra, I. J.

AU - Klee, G. G.

PY - 1990

Y1 - 1990

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AB - We describe a patient whose serum gave consistently low results for thyroxin as measured with the Abbott TDx but normal results by radioimmunoassay. Further clinical and laboratory studies did not support the low TDx results. Anti-thyroxin antibodies did not explain the discordant results, and we found no evidence of heterophilic antibodies in the patient's serum. We were unable to identify the cause of the problem.

KW - Fluorescence polarization immunoassay

KW - analytical error

KW - radioimmunoassay compared

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Anomalous serum thyroxin measurements with the Abbott TDx procedure

Abstract

Keywords

ASJC Scopus subject areas

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