Abstract
We describe a patient whose serum gave consistently low results for thyroxin as measured with the Abbott TDx but normal results by radioimmunoassay. Further clinical and laboratory studies did not support the low TDx results. Anti-thyroxin antibodies did not explain the discordant results, and we found no evidence of heterophilic antibodies in the patient's serum. We were unable to identify the cause of the problem.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1838-1840 |
| Number of pages | 3 |
| Journal | Clinical Chemistry |
| Volume | 36 |
| Issue number | 10 |
| State | Published - 1990 |
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Keywords
- analytical error
- Fluorescence polarization immunoassay
- radioimmunoassay compared
ASJC Scopus subject areas
- Clinical Biochemistry
Cite this
Anomalous serum thyroxin measurements with the Abbott TDx procedure. / Levine, S.; Noth, R.; Loo, A.; Chopra, I. J.; Klee, G. G.
In: Clinical Chemistry, Vol. 36, No. 10, 1990, p. 1838-1840.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Anomalous serum thyroxin measurements with the Abbott TDx procedure
AU - Levine, S.
AU - Noth, R.
AU - Loo, A.
AU - Chopra, I. J.
AU - Klee, G. G.
PY - 1990
Y1 - 1990
N2 - We describe a patient whose serum gave consistently low results for thyroxin as measured with the Abbott TDx but normal results by radioimmunoassay. Further clinical and laboratory studies did not support the low TDx results. Anti-thyroxin antibodies did not explain the discordant results, and we found no evidence of heterophilic antibodies in the patient's serum. We were unable to identify the cause of the problem.
AB - We describe a patient whose serum gave consistently low results for thyroxin as measured with the Abbott TDx but normal results by radioimmunoassay. Further clinical and laboratory studies did not support the low TDx results. Anti-thyroxin antibodies did not explain the discordant results, and we found no evidence of heterophilic antibodies in the patient's serum. We were unable to identify the cause of the problem.
KW - analytical error
KW - Fluorescence polarization immunoassay
KW - radioimmunoassay compared
UR - http://www.scopus.com/inward/record.url?scp=0025155342&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025155342&partnerID=8YFLogxK
M3 - Article
C2 - 2119915
AN - SCOPUS:0025155342
VL - 36
SP - 1838
EP - 1840
JO - Clinical Chemistry
JF - Clinical Chemistry
SN - 0009-9147
IS - 10
ER -