Annualized functional change in Alzheimer's disease participants and normal controls

Myron Weiner, Julie Fields, Linda Hynan, C. M. Cullum

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

The rate of functional change in persons with mild Alzheimer's disease (AD) was compared to that of cognitively normal elderly control subjects. A comparison of annualized rates of change on the Test of Everyday Functional Abilities (TEFA) was carried out, along with a brief measure of instrumental activities of daily living skills, in persons with mild AD (Mini-Mental State Exam score >20) and cognitively normal elderly controls. Persons with AD (N = 30) showed an 8.5 % (3.5 point) annualized decline in TEFA scores over an average of 1.2 years; there was no decline in a group of elderly normal controls (N = 20) over an average of 1.5 years. Persons with mild AD showed functional changes over the course of a year on a direct measure of instrumental activities of daily living; a comparable group of normally aging persons did not.

Original languageEnglish (US)
Pages (from-to)801-806
Number of pages6
JournalClinical Neuropsychologist
Volume22
Issue number5
DOIs
StatePublished - Nov 2007

Keywords

  • Alzheimer's disease
  • Direct measure
  • Functional abilities

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Developmental and Educational Psychology
  • Clinical Psychology
  • Arts and Humanities (miscellaneous)
  • Psychiatry and Mental health

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