Angiotropic large cell lymphoma (intravascular lymphomatosis) occurring after follicular small cleaved cell lymphoma

David K. Carter, Kenneth P. Batts, Piet C. De Groen, Paul J. Kurtin

Research output: Contribution to journalArticle

33 Scopus citations

Abstract

Angiotropic large cell lymphoma is a rare, aggressive type of malignant lymphoma that primarily involves intravascular spaces and most often has clinical manifestations in the skin and central nervous system. Virtually any organ can be affected, however, including the lymph nodes and spleen. Peripheral blood involvement is usually not detectable morphologically. Conventional lymphoma in association with this entity has also been described. Herein we present a case of angiotropic lymphoma of B-cell lineage that affected the liver and skin. Reanalysis of a lymph node specimen that had been excised 3 years previously demonstrated a follicular small cleaved cell lymphoma. To our knowledge, this is the first reported case of possible evolution of follicular lymphoma to large cell lymphoma of angiotropic type.

Original languageEnglish (US)
Pages (from-to)869-873
Number of pages5
JournalMayo Clinic proceedings
Volume71
Issue number9
DOIs
StatePublished - Jan 1 1996

ASJC Scopus subject areas

  • Medicine(all)

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