Angiographic occurrence and clinical correlates of intraluminal coronary artery thrombus: Role of unstable angina

Dennis R. Bresnahan, James L. Davis, David Holmes, Hugh C. Smith

Research output: Contribution to journalArticle

140 Citations (Scopus)

Abstract

The importance of intraluminal coronary artery thrombus in acute myocardial infarction is now recognized. Coronary thrombi, however, may be important in ischemic syndromes other than infarction. The coronary angiograms of 268 consecutive patients undergoing diagnostic angiography were prospectively examined for intracoronary thrombus and form the basis of this study. Of these patients, 29 (11%) (25 men and 4 women) met the criteria for coronary artery thrombus. Of the 29 patients with thrombus, 24 (83%) had unstable angina before angiography. The five remaining patients with thrombus had had a transmural myocardial infarction 3 to 18 months before cardiac catheterization. In 21 patients, the thrombus was distal to a significant stenosis; in 8 it was proximal to or at the site of a significant stenosis. Coronary artery thrombus was identified in 24 (35 %) of 67 patients with unstable angina compared with only 5 (2.5 %) of 201 patients with stable angina (p < 0.0001).

Original languageEnglish (US)
Pages (from-to)285-289
Number of pages5
JournalJournal of the American College of Cardiology
Volume6
Issue number2
DOIs
StatePublished - Jan 1 1985

Fingerprint

Unstable Angina
Coronary Vessels
Thrombosis
Angiography
Pathologic Constriction
Myocardial Infarction
Stable Angina
Cardiac Catheterization
Infarction

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Angiographic occurrence and clinical correlates of intraluminal coronary artery thrombus : Role of unstable angina. / Bresnahan, Dennis R.; Davis, James L.; Holmes, David; Smith, Hugh C.

In: Journal of the American College of Cardiology, Vol. 6, No. 2, 01.01.1985, p. 285-289.

Research output: Contribution to journalArticle

@article{3aa860cd22c848bfbb16943c4795a5b1,
title = "Angiographic occurrence and clinical correlates of intraluminal coronary artery thrombus: Role of unstable angina",
abstract = "The importance of intraluminal coronary artery thrombus in acute myocardial infarction is now recognized. Coronary thrombi, however, may be important in ischemic syndromes other than infarction. The coronary angiograms of 268 consecutive patients undergoing diagnostic angiography were prospectively examined for intracoronary thrombus and form the basis of this study. Of these patients, 29 (11{\%}) (25 men and 4 women) met the criteria for coronary artery thrombus. Of the 29 patients with thrombus, 24 (83{\%}) had unstable angina before angiography. The five remaining patients with thrombus had had a transmural myocardial infarction 3 to 18 months before cardiac catheterization. In 21 patients, the thrombus was distal to a significant stenosis; in 8 it was proximal to or at the site of a significant stenosis. Coronary artery thrombus was identified in 24 (35 {\%}) of 67 patients with unstable angina compared with only 5 (2.5 {\%}) of 201 patients with stable angina (p < 0.0001).",
author = "Bresnahan, {Dennis R.} and Davis, {James L.} and David Holmes and Smith, {Hugh C.}",
year = "1985",
month = "1",
day = "1",
doi = "10.1016/S0735-1097(85)80161-3",
language = "English (US)",
volume = "6",
pages = "285--289",
journal = "Journal of the American College of Cardiology",
issn = "0735-1097",
publisher = "Elsevier USA",
number = "2",

}

TY - JOUR

T1 - Angiographic occurrence and clinical correlates of intraluminal coronary artery thrombus

T2 - Role of unstable angina

AU - Bresnahan, Dennis R.

AU - Davis, James L.

AU - Holmes, David

AU - Smith, Hugh C.

PY - 1985/1/1

Y1 - 1985/1/1

N2 - The importance of intraluminal coronary artery thrombus in acute myocardial infarction is now recognized. Coronary thrombi, however, may be important in ischemic syndromes other than infarction. The coronary angiograms of 268 consecutive patients undergoing diagnostic angiography were prospectively examined for intracoronary thrombus and form the basis of this study. Of these patients, 29 (11%) (25 men and 4 women) met the criteria for coronary artery thrombus. Of the 29 patients with thrombus, 24 (83%) had unstable angina before angiography. The five remaining patients with thrombus had had a transmural myocardial infarction 3 to 18 months before cardiac catheterization. In 21 patients, the thrombus was distal to a significant stenosis; in 8 it was proximal to or at the site of a significant stenosis. Coronary artery thrombus was identified in 24 (35 %) of 67 patients with unstable angina compared with only 5 (2.5 %) of 201 patients with stable angina (p < 0.0001).

AB - The importance of intraluminal coronary artery thrombus in acute myocardial infarction is now recognized. Coronary thrombi, however, may be important in ischemic syndromes other than infarction. The coronary angiograms of 268 consecutive patients undergoing diagnostic angiography were prospectively examined for intracoronary thrombus and form the basis of this study. Of these patients, 29 (11%) (25 men and 4 women) met the criteria for coronary artery thrombus. Of the 29 patients with thrombus, 24 (83%) had unstable angina before angiography. The five remaining patients with thrombus had had a transmural myocardial infarction 3 to 18 months before cardiac catheterization. In 21 patients, the thrombus was distal to a significant stenosis; in 8 it was proximal to or at the site of a significant stenosis. Coronary artery thrombus was identified in 24 (35 %) of 67 patients with unstable angina compared with only 5 (2.5 %) of 201 patients with stable angina (p < 0.0001).

UR - http://www.scopus.com/inward/record.url?scp=0021864422&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021864422&partnerID=8YFLogxK

U2 - 10.1016/S0735-1097(85)80161-3

DO - 10.1016/S0735-1097(85)80161-3

M3 - Article

C2 - 4019915

AN - SCOPUS:0021864422

VL - 6

SP - 285

EP - 289

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

SN - 0735-1097

IS - 2

ER -