TY - JOUR
T1 - Angiographic occurrence and clinical correlates of intraluminal coronary artery thrombus
T2 - Role of unstable angina
AU - Bresnahan, Dennis R.
AU - Davis, James L.
AU - Holmes, David R.
AU - Smith, Hugh C.
PY - 1985
Y1 - 1985
N2 - The importance of intraluminal coronary artery thrombus in acute myocardial infarction is now recognized. Coronary thrombi, however, may be important in ischemic syndromes other than infarction. The coronary angiograms of 268 consecutive patients undergoing diagnostic angiography were prospectively examined for intracoronary thrombus and form the basis of this study. Of these patients, 29 (11%) (25 men and 4 women) met the criteria for coronary artery thrombus. Of the 29 patients with thrombus, 24 (83%) had unstable angina before angiography. The five remaining patients with thrombus had had a transmural myocardial infarction 3 to 18 months before cardiac catheterization. In 21 patients, the thrombus was distal to a significant stenosis; in 8 it was proximal to or at the site of a significant stenosis. Coronary artery thrombus was identified in 24 (35 %) of 67 patients with unstable angina compared with only 5 (2.5 %) of 201 patients with stable angina (p < 0.0001).
AB - The importance of intraluminal coronary artery thrombus in acute myocardial infarction is now recognized. Coronary thrombi, however, may be important in ischemic syndromes other than infarction. The coronary angiograms of 268 consecutive patients undergoing diagnostic angiography were prospectively examined for intracoronary thrombus and form the basis of this study. Of these patients, 29 (11%) (25 men and 4 women) met the criteria for coronary artery thrombus. Of the 29 patients with thrombus, 24 (83%) had unstable angina before angiography. The five remaining patients with thrombus had had a transmural myocardial infarction 3 to 18 months before cardiac catheterization. In 21 patients, the thrombus was distal to a significant stenosis; in 8 it was proximal to or at the site of a significant stenosis. Coronary artery thrombus was identified in 24 (35 %) of 67 patients with unstable angina compared with only 5 (2.5 %) of 201 patients with stable angina (p < 0.0001).
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U2 - 10.1016/S0735-1097(85)80161-3
DO - 10.1016/S0735-1097(85)80161-3
M3 - Article
C2 - 4019915
AN - SCOPUS:0021864422
SN - 0735-1097
VL - 6
SP - 285
EP - 289
JO - Journal of the American College of Cardiology
JF - Journal of the American College of Cardiology
IS - 2
ER -