Angina pectoris with a normal coronary angiogram

Eric H. Yang, Amir Lerman

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Angina in the setting of a normal angiogram (NOCAD) occurs in 20-30% of patients undergoing coronary angiography. The etiologies of NOCAD can be anatomically classified into three groups: epicardial disease, coronary microvascular dysfunction, and noncoronary disease. Epicardial disease resulting in NOCAD includes endothelial dysfunction, coronary artery spasm, and coronary artery bridging. Microvascular dysfunction maybe secondary to hypertension, cardiomyopathy, infiltrative disease, valvular disease, or idiopathic. Noncoronary artery disease states involving other organs systems such as the pulmonary, gastrointestinal, or musculoskeletal systems can also result in NOCAD. This review focuses on the coronary etiologies of NOCAD. The pathophysiology of disease is discussed as well as a systematic diagnostic strategy. Potential therapeutic options and prognosis are also reviewed.

Original languageEnglish (US)
Pages (from-to)17-25
Number of pages9
JournalHerz
Volume30
Issue number1
DOIs
StatePublished - Feb 2005

Fingerprint

Angina Pectoris
Angiography
Coronary Vessels
Musculoskeletal System
Spasm
Coronary Angiography
Cardiomyopathies
Coronary Disease
Arteries
Hypertension
Lung

Keywords

  • Angina
  • Coronary spasm
  • Endothelial dysfunction
  • Microvascular dysfunction
  • Normal angiogram

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Angina pectoris with a normal coronary angiogram. / Yang, Eric H.; Lerman, Amir.

In: Herz, Vol. 30, No. 1, 02.2005, p. 17-25.

Research output: Contribution to journalArticle

Yang, Eric H. ; Lerman, Amir. / Angina pectoris with a normal coronary angiogram. In: Herz. 2005 ; Vol. 30, No. 1. pp. 17-25.
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