TY - JOUR
T1 - Aneurysmal Subarachnoid Hemorrhage
T2 - Unanswered Questions
AU - Rabinstein, Alejandro A.
AU - Lanzino, Giuseppe
N1 - Publisher Copyright:
© 2018 Elsevier Inc.
PY - 2018/4
Y1 - 2018/4
N2 - Optimizing outcomes after aneurysmal subarachnoid hemorrhage remains a challenge for neurosurgeons and neurointensivists alike. Although we have learned a lot about the pathophysiology of this disease, many clinical questions are still unanswered. In this review, the authors discuss some of these questions, including the current diagnostic value of lumbar puncture in patients with negative computed tomography scans, the treatment value of blood pressure reduction and antifibrinolytics for prevention of early rebleeding, the indication for antiseizure medications, the optimal management of hydrocephalus and intracranial pressure, the role of clipping, and the options for diagnosis and treatment of delayed cerebral ischemia.
AB - Optimizing outcomes after aneurysmal subarachnoid hemorrhage remains a challenge for neurosurgeons and neurointensivists alike. Although we have learned a lot about the pathophysiology of this disease, many clinical questions are still unanswered. In this review, the authors discuss some of these questions, including the current diagnostic value of lumbar puncture in patients with negative computed tomography scans, the treatment value of blood pressure reduction and antifibrinolytics for prevention of early rebleeding, the indication for antiseizure medications, the optimal management of hydrocephalus and intracranial pressure, the role of clipping, and the options for diagnosis and treatment of delayed cerebral ischemia.
KW - Aneurysm
KW - Delayed cerebral ischemia
KW - Hydrocephalus
KW - Subarachnoid hemorrhage
KW - Vasospasm
UR - http://www.scopus.com/inward/record.url?scp=85042768013&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85042768013&partnerID=8YFLogxK
U2 - 10.1016/j.nec.2018.01.001
DO - 10.1016/j.nec.2018.01.001
M3 - Review article
C2 - 29502715
AN - SCOPUS:85042768013
SN - 1042-3680
VL - 29
SP - 255
EP - 262
JO - Neurosurgery clinics of North America
JF - Neurosurgery clinics of North America
IS - 2
ER -