Anesthetic-Related Neurotoxicity and Neuroimaging in Children: A Call for Conversation

Kara A. Bjur; Eric T. Payne; Michael E. Nemergut; Danqing Hu; Randall P. Flick

doi:10.1177/0883073817691696

Anesthetic-Related Neurotoxicity and Neuroimaging in Children: A Call for Conversation

Kara A. Bjur, Eric T. Payne, Michael E. Nemergut, Danqing Hu, Randall P. Flick

Anesthesiology

Research output: Contribution to journal › Review article › peer-review

21 Scopus citations

Abstract

Each year millions of young children undergo procedures requiring sedation or general anesthesia. An increasing proportion of the anesthetics used are provided to optimize diagnostic imaging studies such as magnetic resonance imaging. Concern regarding the neurotoxicity of sedatives and anesthetics has prompted the US Food and Drug Administration to change labeling of anesthetics and sedative agents warning against repeated or prolonged exposure in young children. This review aims to summarize the risk of anesthesia in children with an emphasis on anesthetic-related neurotoxicity, acknowledge the value of pediatric neuroimaging, and address this call for conversation.

Original language	English (US)
Pages (from-to)	594-602
Number of pages	9
Journal	Journal of child neurology
Volume	32
Issue number	6
DOIs	https://doi.org/10.1177/0883073817691696
State	Published - May 1 2017

Keywords

anesthesia
anesthetic
children
diagnostic imaging
magnetic resonance imaging
neurodevelopment
neuroimaging
neurotoxicity
sedation

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Clinical Neurology

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10.1177/0883073817691696

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abstract = "Each year millions of young children undergo procedures requiring sedation or general anesthesia. An increasing proportion of the anesthetics used are provided to optimize diagnostic imaging studies such as magnetic resonance imaging. Concern regarding the neurotoxicity of sedatives and anesthetics has prompted the US Food and Drug Administration to change labeling of anesthetics and sedative agents warning against repeated or prolonged exposure in young children. This review aims to summarize the risk of anesthesia in children with an emphasis on anesthetic-related neurotoxicity, acknowledge the value of pediatric neuroimaging, and address this call for conversation.",

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AU - Hu, Danqing

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Anesthetic-Related Neurotoxicity and Neuroimaging in Children: A Call for Conversation

Abstract

Keywords

ASJC Scopus subject areas

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