Anesthetic implications for patients with Segawa syndrome

Study objective To characterize the perioperative course of patients with Segawa syndrome undergoing anesthetic management. Design Retrospective observational case study. Setting Large tertiary medical center. Patients Patients with Segawa syndrome who underwent procedures requiring anesthetic management at our institution from January 1, 2004, through July 31, 2015. Measurements The health records of patients with Segawa syndrome. Main results Twelve patients with Segawa syndrome underwent 25 procedures requiring anesthetic management, including 20 operations with general anesthesia. Succinylcholine was administered in 6 cases and nondepolarizing neuromuscular blockers in 5 cases, all without adverse effects. Perioperative complications were unrelated to anesthetic management or underlying neurologic condition. In 16 operations, the patients were receiving levodopa therapy at the time of the procedure. Conclusions In this cohort, patients with Segawa syndrome tolerated the anesthetic management, including neuromuscular blocker administration. Although these patients are frequently receiving levodopa therapy, no associated complications were noted.