Abstract
The purpose of the study was to compare hemodynamics and postanesthetic tolerability of sevoflurane versus thiopental in electroconvulsive therapy (ECT). The design was a randomized double-blind trial in the ECT suite of a tertiary referral medical center. Thirty-one patients were randomized to either sevoflurane or thiopental induction of anesthesia for up to 6 of each subject's ECT treatments. Measurements included hemodynamics (heart rate and blood pressure), arrhythmias, posttreatment orientation, time to first breath, and posttreatment side effects. Sevoflurane compared favorably with thiopental in terms of hemodynamics and time to first breath, although there was a slightly nonsignificant trend toward faster recovery with sevoflurane. Sevoflurane was associated with significantly better postictal orientation 20 minutes after the treatment. We conclude that inhalational anesthesia with sevoflurane presents a well-tolerated alternative for ECT anesthesia.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 236-238 |
| Number of pages | 3 |
| Journal | Journal of ECT |
| Volume | 23 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 2007 |
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Keywords
- Anesthesia
- Electroconvulsive therapy
- Sevoflurane
- Thiopental
ASJC Scopus subject areas
- Psychiatry and Mental health
Cite this
Anesthesia outcomes in a randomized double-blind trial of sevoflurane and thiopental for induction of general anesthesia in electroconvulsive therapy. / Rasmussen, Keith G.; Laurila, Daniel R.; Brady, Bret M.; Lewis, Christy L.; Niemeyer, Kimberly D.; Sun, Norazlina M.; Marienau, Marie E S; Hooten, W. Michael; Schroeder, Darrell R.; Spackman, Thomas M.
In: Journal of ECT, Vol. 23, No. 4, 12.2007, p. 236-238.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Anesthesia outcomes in a randomized double-blind trial of sevoflurane and thiopental for induction of general anesthesia in electroconvulsive therapy
AU - Rasmussen, Keith G.
AU - Laurila, Daniel R.
AU - Brady, Bret M.
AU - Lewis, Christy L.
AU - Niemeyer, Kimberly D.
AU - Sun, Norazlina M.
AU - Marienau, Marie E S
AU - Hooten, W. Michael
AU - Schroeder, Darrell R.
AU - Spackman, Thomas M.
PY - 2007/12
Y1 - 2007/12
N2 - The purpose of the study was to compare hemodynamics and postanesthetic tolerability of sevoflurane versus thiopental in electroconvulsive therapy (ECT). The design was a randomized double-blind trial in the ECT suite of a tertiary referral medical center. Thirty-one patients were randomized to either sevoflurane or thiopental induction of anesthesia for up to 6 of each subject's ECT treatments. Measurements included hemodynamics (heart rate and blood pressure), arrhythmias, posttreatment orientation, time to first breath, and posttreatment side effects. Sevoflurane compared favorably with thiopental in terms of hemodynamics and time to first breath, although there was a slightly nonsignificant trend toward faster recovery with sevoflurane. Sevoflurane was associated with significantly better postictal orientation 20 minutes after the treatment. We conclude that inhalational anesthesia with sevoflurane presents a well-tolerated alternative for ECT anesthesia.
AB - The purpose of the study was to compare hemodynamics and postanesthetic tolerability of sevoflurane versus thiopental in electroconvulsive therapy (ECT). The design was a randomized double-blind trial in the ECT suite of a tertiary referral medical center. Thirty-one patients were randomized to either sevoflurane or thiopental induction of anesthesia for up to 6 of each subject's ECT treatments. Measurements included hemodynamics (heart rate and blood pressure), arrhythmias, posttreatment orientation, time to first breath, and posttreatment side effects. Sevoflurane compared favorably with thiopental in terms of hemodynamics and time to first breath, although there was a slightly nonsignificant trend toward faster recovery with sevoflurane. Sevoflurane was associated with significantly better postictal orientation 20 minutes after the treatment. We conclude that inhalational anesthesia with sevoflurane presents a well-tolerated alternative for ECT anesthesia.
KW - Anesthesia
KW - Electroconvulsive therapy
KW - Sevoflurane
KW - Thiopental
UR - http://www.scopus.com/inward/record.url?scp=37349059981&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=37349059981&partnerID=8YFLogxK
U2 - 10.1097/yct.0b013e318136e1b4
DO - 10.1097/yct.0b013e318136e1b4
M3 - Article
C2 - 18090695
AN - SCOPUS:37349059981
VL - 23
SP - 236
EP - 238
JO - Journal of ECT
JF - Journal of ECT
SN - 1095-0680
IS - 4
ER -