Andropause: Symptom management for prostate cancer patients treated with hormonal ablation

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

Andropause, or the age-related decline in serum testosterone, has become a popular topic in the medical literature over the past several years. Andropause includes a constellation of symptoms related to lack of androgens, including diminished libido, decreased generalized feeling of well-being, osteoporosis, and a host of other symptoms. The andropause syndrome is very prominent in men undergoing hormonal ablation therapy for prostate cancer. Most significant in this population are the side effects of hot flashes, anemia, gynecomastia, depression, cognitive decline, sarcopenia, a decreased overall quality of life, sexual dysfunction, and osteoporosis with subsequent bone fractures. The concept of andropause in prostate cancer patients is poorly represented in the literature. In this article, we review the current literature on the symptoms, signs, and possible therapies available to men who cannot take replacement testosterone.

Original languageEnglish (US)
Pages (from-to)474-487
Number of pages14
JournalOncologist
Volume8
Issue number5
DOIs
StatePublished - 2003

Fingerprint

Andropause
Prostatic Neoplasms
Osteoporosis
Testosterone
Hot Flashes
Sarcopenia
Gynecomastia
Libido
Bone Fractures
Androgens
Signs and Symptoms
Anemia
Emotions
Quality of Life
Depression
Therapeutics
Serum
Population

Keywords

  • Androgens
  • Antineoplastic agents, hormonal
  • Hot flashes
  • Impotence
  • Osteoporosis
  • Prostatic neoplasms
  • Quality of life

ASJC Scopus subject areas

  • Cancer Research
  • Hematology

Cite this

Andropause : Symptom management for prostate cancer patients treated with hormonal ablation. / Thompson, Carrie A; Shanafelt, Tait D.; Loprinzi, Charles Lawrence.

In: Oncologist, Vol. 8, No. 5, 2003, p. 474-487.

Research output: Contribution to journalArticle

@article{69512fc5c7c94c75a2db424576b3554f,
title = "Andropause: Symptom management for prostate cancer patients treated with hormonal ablation",
abstract = "Andropause, or the age-related decline in serum testosterone, has become a popular topic in the medical literature over the past several years. Andropause includes a constellation of symptoms related to lack of androgens, including diminished libido, decreased generalized feeling of well-being, osteoporosis, and a host of other symptoms. The andropause syndrome is very prominent in men undergoing hormonal ablation therapy for prostate cancer. Most significant in this population are the side effects of hot flashes, anemia, gynecomastia, depression, cognitive decline, sarcopenia, a decreased overall quality of life, sexual dysfunction, and osteoporosis with subsequent bone fractures. The concept of andropause in prostate cancer patients is poorly represented in the literature. In this article, we review the current literature on the symptoms, signs, and possible therapies available to men who cannot take replacement testosterone.",
keywords = "Androgens, Antineoplastic agents, hormonal, Hot flashes, Impotence, Osteoporosis, Prostatic neoplasms, Quality of life",
author = "Thompson, {Carrie A} and Shanafelt, {Tait D.} and Loprinzi, {Charles Lawrence}",
year = "2003",
doi = "10.1634/theoncologist.8-5-474",
language = "English (US)",
volume = "8",
pages = "474--487",
journal = "Oncologist",
issn = "1083-7159",
publisher = "AlphaMed Press",
number = "5",

}

TY - JOUR

T1 - Andropause

T2 - Symptom management for prostate cancer patients treated with hormonal ablation

AU - Thompson, Carrie A

AU - Shanafelt, Tait D.

AU - Loprinzi, Charles Lawrence

PY - 2003

Y1 - 2003

N2 - Andropause, or the age-related decline in serum testosterone, has become a popular topic in the medical literature over the past several years. Andropause includes a constellation of symptoms related to lack of androgens, including diminished libido, decreased generalized feeling of well-being, osteoporosis, and a host of other symptoms. The andropause syndrome is very prominent in men undergoing hormonal ablation therapy for prostate cancer. Most significant in this population are the side effects of hot flashes, anemia, gynecomastia, depression, cognitive decline, sarcopenia, a decreased overall quality of life, sexual dysfunction, and osteoporosis with subsequent bone fractures. The concept of andropause in prostate cancer patients is poorly represented in the literature. In this article, we review the current literature on the symptoms, signs, and possible therapies available to men who cannot take replacement testosterone.

AB - Andropause, or the age-related decline in serum testosterone, has become a popular topic in the medical literature over the past several years. Andropause includes a constellation of symptoms related to lack of androgens, including diminished libido, decreased generalized feeling of well-being, osteoporosis, and a host of other symptoms. The andropause syndrome is very prominent in men undergoing hormonal ablation therapy for prostate cancer. Most significant in this population are the side effects of hot flashes, anemia, gynecomastia, depression, cognitive decline, sarcopenia, a decreased overall quality of life, sexual dysfunction, and osteoporosis with subsequent bone fractures. The concept of andropause in prostate cancer patients is poorly represented in the literature. In this article, we review the current literature on the symptoms, signs, and possible therapies available to men who cannot take replacement testosterone.

KW - Androgens

KW - Antineoplastic agents, hormonal

KW - Hot flashes

KW - Impotence

KW - Osteoporosis

KW - Prostatic neoplasms

KW - Quality of life

UR - http://www.scopus.com/inward/record.url?scp=0141957526&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0141957526&partnerID=8YFLogxK

U2 - 10.1634/theoncologist.8-5-474

DO - 10.1634/theoncologist.8-5-474

M3 - Article

C2 - 14530501

AN - SCOPUS:0141957526

VL - 8

SP - 474

EP - 487

JO - Oncologist

JF - Oncologist

SN - 1083-7159

IS - 5

ER -