Abstract
The term androgen-independent cancer has now become a misnomer. Given that the androgen receptor can be activated by even low androgen concentrations or via protein modifications or other protein-protein interactions, a growing prostate cancer has the chance of assuming an androgen depletion-independent state, without necessarily bypassing the androgen signaling processes. It is thus suggested that "androgen-independent (Al)" cancer should be more accurately termed "androgen depletion-independent (ADI)" cancer.
Original language | English (US) |
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Pages (from-to) | 4-5 |
Number of pages | 2 |
Journal | Cancer Biology and Therapy |
Volume | 4 |
Issue number | 1 |
DOIs | |
State | Published - Jan 2005 |
ASJC Scopus subject areas
- Molecular Medicine
- Oncology
- Pharmacology
- Cancer Research