Androgens and prostate cancer: Are the descriptors valid?

Pradip Roy-Burman, Donald J. Tindall, Diane M. Robins, Norman M. Greenberg, Mary J C Hendrix, Suresh Mohla, Robert H. Getzenberg, John T. Isaacs, Kenneth J. Pienta

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

The term androgen-independent cancer has now become a misnomer. Given that the androgen receptor can be activated by even low androgen concentrations or via protein modifications or other protein-protein interactions, a growing prostate cancer has the chance of assuming an androgen depletion-independent state, without necessarily bypassing the androgen signaling processes. It is thus suggested that "androgen-independent (Al)" cancer should be more accurately termed "androgen depletion-independent (ADI)" cancer.

Original languageEnglish (US)
Pages (from-to)4-5
Number of pages2
JournalCancer Biology and Therapy
Volume4
Issue number1
StatePublished - Jan 2005

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Androgens
Prostatic Neoplasms
Neoplasms
Proteins
Androgen Receptors

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Roy-Burman, P., Tindall, D. J., Robins, D. M., Greenberg, N. M., Hendrix, M. J. C., Mohla, S., ... Pienta, K. J. (2005). Androgens and prostate cancer: Are the descriptors valid? Cancer Biology and Therapy, 4(1), 4-5.

Androgens and prostate cancer : Are the descriptors valid? / Roy-Burman, Pradip; Tindall, Donald J.; Robins, Diane M.; Greenberg, Norman M.; Hendrix, Mary J C; Mohla, Suresh; Getzenberg, Robert H.; Isaacs, John T.; Pienta, Kenneth J.

In: Cancer Biology and Therapy, Vol. 4, No. 1, 01.2005, p. 4-5.

Research output: Contribution to journalArticle

Roy-Burman, P, Tindall, DJ, Robins, DM, Greenberg, NM, Hendrix, MJC, Mohla, S, Getzenberg, RH, Isaacs, JT & Pienta, KJ 2005, 'Androgens and prostate cancer: Are the descriptors valid?', Cancer Biology and Therapy, vol. 4, no. 1, pp. 4-5.
Roy-Burman P, Tindall DJ, Robins DM, Greenberg NM, Hendrix MJC, Mohla S et al. Androgens and prostate cancer: Are the descriptors valid? Cancer Biology and Therapy. 2005 Jan;4(1):4-5.
Roy-Burman, Pradip ; Tindall, Donald J. ; Robins, Diane M. ; Greenberg, Norman M. ; Hendrix, Mary J C ; Mohla, Suresh ; Getzenberg, Robert H. ; Isaacs, John T. ; Pienta, Kenneth J. / Androgens and prostate cancer : Are the descriptors valid?. In: Cancer Biology and Therapy. 2005 ; Vol. 4, No. 1. pp. 4-5.
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