TY - JOUR
T1 - Androgen deprivation therapy-associated vasomotor symptoms
AU - Jones, Jason M.
AU - Kohli, Manish
AU - Loprinzi, Charles L.
PY - 2012/3
Y1 - 2012/3
N2 - Androgen deprivation therapy (ADT) is widely used as standard therapy in the treatment of locally advanced and metastatic prostate cancer. While efficacious, ADT is associated with multiple side effects, including decreased libido, erectile dysfunction, diabetes, loss of muscle tone and altered body composition, osteoporosis, lipid changes, memory loss, gynecomastia and hot flashes. The breadth of literature for the treatment of hot flashes is much smaller in men than that in women. While hormonal therapy of hot flashes has been shown to be effective, multiple non-hormonal medications and treatment methods have also been developed. This article reviews current options for the treatment of hot flashes in patients taking ADT.
AB - Androgen deprivation therapy (ADT) is widely used as standard therapy in the treatment of locally advanced and metastatic prostate cancer. While efficacious, ADT is associated with multiple side effects, including decreased libido, erectile dysfunction, diabetes, loss of muscle tone and altered body composition, osteoporosis, lipid changes, memory loss, gynecomastia and hot flashes. The breadth of literature for the treatment of hot flashes is much smaller in men than that in women. While hormonal therapy of hot flashes has been shown to be effective, multiple non-hormonal medications and treatment methods have also been developed. This article reviews current options for the treatment of hot flashes in patients taking ADT.
KW - hot flashes
KW - vandrogen deprivation therapy
KW - vasomotor symptoms
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U2 - 10.1038/aja.2011.101
DO - 10.1038/aja.2011.101
M3 - Review article
C2 - 22286861
AN - SCOPUS:84863393685
SN - 1008-682X
VL - 14
SP - 193
EP - 197
JO - Asian Journal of Andrology
JF - Asian Journal of Andrology
IS - 2
ER -