AnalyzeNNLS: Magnetic resonance multiexponential decay image analysis

Thorarin A. Bjarnason, J. Ross Mitchell

Research output: Contribution to journalArticlepeer-review

21 Scopus citations

Abstract

Exponential decays are fundamental to magnetic resonance imaging, yet adequately sampling and analyzing multiexponential decays is rarely attempted. The advantage of multiexponential analysis is the quantification of sub-voxel structure caused by water compartmentalization, with application as a non-invasive imaging biomarker for myelin. We have developed AnalyzeNNLS, software designed specifically for multiexponential decay image analysis that has a user-friendly graphical user interface and can analyze data from many MR manufacturers. AnalyzeNNLS is a simple, platform independent analysis tool that was created using the extensive mathematical and visualization libraries in Matlab, and released as open source code allowing scientists to evaluate, scrutinize, improve, and expand.

Original languageEnglish (US)
Pages (from-to)200-204
Number of pages5
JournalJournal of Magnetic Resonance
Volume206
Issue number2
DOIs
StatePublished - Oct 1 2010

Keywords

  • Magnetic resonance
  • Matlab
  • Multiexponential analysis
  • Quantitative T
  • Visualization

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Nuclear and High Energy Physics
  • Condensed Matter Physics

Fingerprint Dive into the research topics of 'AnalyzeNNLS: Magnetic resonance multiexponential decay image analysis'. Together they form a unique fingerprint.

Cite this