@inproceedings{a326f4cc3673485ba6b03a37db866926,
title = "Analysis of left atrial respiratory and cardiac motion for cardiac ablation therapy",
abstract = "Cardiac ablation therapy is often guided by models built from preoperative computed tomography (CT) or magnetic resonance imaging (MRI) scans. One of the challenges in guiding a procedure from a preoperative model is properly synching the preoperative models with cardiac and respiratory motion through computational motion models. In this paper, we describe a methodology for evaluating cardiac and respiratory motion in the left atrium and pulmonary veins of a beating canine heart. Cardiac catheters were used to place metal clips within and near the pulmonary veins and left atrial appendage under fluoroscopic and ultrasound guidance and a contrast-enhanced, 64-slice multidetector CT scan was collected with the clips in place. Each clip was segmented from the CT scan at each of the five phases of the cardiac cycle at both end-inspiration and end-expiration. The centroid of each segmented clip was computed and used to evaluate both cardiac and respiratory motion of the left atrium. A total of three canine studies were completed, with 4 clips analyzed in the first study, 5 clips in the second study, and 2 clips in the third study. Mean respiratory displacement was 0.2±1.8 mm in the medial/lateral direction, 4.7±4.4 mm in the anterior/posterior direction (moving anterior on inspiration), and 9.0±5.0 mm superior/inferior (moving inferior with inspiration). At end inspiration, the mean left atrial cardiac motion at the clip locations was 1.5±1.3 mm in the medial/lateral direction, and 2.1±2.0 mm in the anterior/posterior and 1.3±1.2 mm superior/inferior directions. At end expiration, the mean left atrial cardiac motion at the clip locations was 2.0±1.5 mm in the medial/lateral direction, 3.0±1.8 mm in the anterior/posterior direction, and 1.5±1.5 mm in the superior/inferior directions.",
author = "Rettmann, {M. E.} and Holmes, {D. R.} and Johnson, {S. B.} and Lehmann, {H. I.} and Robb, {R. A.} and Packer, {D. L.}",
note = "Publisher Copyright: {\textcopyright} 2015 SPIE.; Medical Imaging 2015: Image-Guided Procedures, Robotic Interventions, and Modeling ; Conference date: 22-02-2015 Through 24-02-2015",
year = "2015",
doi = "10.1117/12.2081209",
language = "English (US)",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
publisher = "SPIE",
editor = "Webster, {Robert J.} and Yaniv, {Ziv R.}",
booktitle = "Medical Imaging 2015",
}