Analysis of circadian rhythms by fitting a least squares sine curve

D. S. Hickey, J. L. Kirkland, S. B. Lucas, M. Lye

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

A method that fits a least squares sine curve to both point and averaged time series data is described. The method includes a full regression analysis and extends the current "cosinor" approach. Developments include estimation of the linear trend and fitting secondary wave forms.

Original languageEnglish (US)
Pages (from-to)217-223
Number of pages7
JournalComputers in Biology and Medicine
Volume14
Issue number2
DOIs
StatePublished - 1984

Keywords

  • Circadian
  • Integrated
  • Least-squares
  • Rhythm
  • Sinusoidal
  • Time-series

ASJC Scopus subject areas

  • Computer Science Applications
  • Health Informatics

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