Analysis and interpretation of results based on patient-reported outcomes

Jeff A Sloan, Amylou Dueck, Pennifer A. Erickson, Harry Guess, Dennis A. Revicki, Nancy C. Santanello

Research output: Contribution to journalArticle

31 Citations (Scopus)

Abstract

This article is part of a series of manuscripts dealing with the incorporation of patient-reported outcomes (PROs) into clinical trials. The issues dealt with in this manuscript concern the common pitfalls to avoid in statistical analysis and interpretation of PROs. Specifically, the questions addressed by this manuscript involve the analysis pitfalls with PRO data in clinical trials and how can they be avoided (e.g.,missing data, multiplicity, null results etc.). The manuscript provides key literature for existing resources and proposes new guidelines.

Original languageEnglish (US)
JournalValue in Health
Volume10
Issue numberSUPPL. 2
DOIs
StatePublished - Nov 2007

Fingerprint

Manuscripts
interpretation
Clinical Trials
statistical analysis
resources
Guidelines
Patient Reported Outcome Measures
literature

Keywords

  • Clinical significance
  • Minimally important difference
  • Missing data
  • Patient-reported outcomes
  • Statistical analysis

ASJC Scopus subject areas

  • Nursing(all)
  • Health(social science)
  • Health Professions(all)

Cite this

Analysis and interpretation of results based on patient-reported outcomes. / Sloan, Jeff A; Dueck, Amylou; Erickson, Pennifer A.; Guess, Harry; Revicki, Dennis A.; Santanello, Nancy C.

In: Value in Health, Vol. 10, No. SUPPL. 2, 11.2007.

Research output: Contribution to journalArticle

Sloan, Jeff A ; Dueck, Amylou ; Erickson, Pennifer A. ; Guess, Harry ; Revicki, Dennis A. ; Santanello, Nancy C. / Analysis and interpretation of results based on patient-reported outcomes. In: Value in Health. 2007 ; Vol. 10, No. SUPPL. 2.
@article{d713efab2c5e41959ae3de808377f15f,
title = "Analysis and interpretation of results based on patient-reported outcomes",
abstract = "This article is part of a series of manuscripts dealing with the incorporation of patient-reported outcomes (PROs) into clinical trials. The issues dealt with in this manuscript concern the common pitfalls to avoid in statistical analysis and interpretation of PROs. Specifically, the questions addressed by this manuscript involve the analysis pitfalls with PRO data in clinical trials and how can they be avoided (e.g.,missing data, multiplicity, null results etc.). The manuscript provides key literature for existing resources and proposes new guidelines.",
keywords = "Clinical significance, Minimally important difference, Missing data, Patient-reported outcomes, Statistical analysis",
author = "Sloan, {Jeff A} and Amylou Dueck and Erickson, {Pennifer A.} and Harry Guess and Revicki, {Dennis A.} and Santanello, {Nancy C.}",
year = "2007",
month = "11",
doi = "10.1111/j.1524-4733.2007.00273.x",
language = "English (US)",
volume = "10",
journal = "Value in Health",
issn = "1098-3015",
publisher = "Elsevier Limited",
number = "SUPPL. 2",

}

TY - JOUR

T1 - Analysis and interpretation of results based on patient-reported outcomes

AU - Sloan, Jeff A

AU - Dueck, Amylou

AU - Erickson, Pennifer A.

AU - Guess, Harry

AU - Revicki, Dennis A.

AU - Santanello, Nancy C.

PY - 2007/11

Y1 - 2007/11

N2 - This article is part of a series of manuscripts dealing with the incorporation of patient-reported outcomes (PROs) into clinical trials. The issues dealt with in this manuscript concern the common pitfalls to avoid in statistical analysis and interpretation of PROs. Specifically, the questions addressed by this manuscript involve the analysis pitfalls with PRO data in clinical trials and how can they be avoided (e.g.,missing data, multiplicity, null results etc.). The manuscript provides key literature for existing resources and proposes new guidelines.

AB - This article is part of a series of manuscripts dealing with the incorporation of patient-reported outcomes (PROs) into clinical trials. The issues dealt with in this manuscript concern the common pitfalls to avoid in statistical analysis and interpretation of PROs. Specifically, the questions addressed by this manuscript involve the analysis pitfalls with PRO data in clinical trials and how can they be avoided (e.g.,missing data, multiplicity, null results etc.). The manuscript provides key literature for existing resources and proposes new guidelines.

KW - Clinical significance

KW - Minimally important difference

KW - Missing data

KW - Patient-reported outcomes

KW - Statistical analysis

UR - http://www.scopus.com/inward/record.url?scp=36048959818&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=36048959818&partnerID=8YFLogxK

U2 - 10.1111/j.1524-4733.2007.00273.x

DO - 10.1111/j.1524-4733.2007.00273.x

M3 - Article

C2 - 17995469

AN - SCOPUS:36048959818

VL - 10

JO - Value in Health

JF - Value in Health

SN - 1098-3015

IS - SUPPL. 2

ER -