@inproceedings{c37cc3d37587417981c848eec6008729,
title = "An RDF/OWL knowledge base for query answering and decision support in clinical pharmacogenetics",
abstract = "Genetic testing for personalizing pharmacotherapy is bound to become an important part of clinical routine. To address associated issues with data management and quality, we are creating a semantic knowledge base for clinical pharmacogenetics. The knowledge base is made up of three components: an expressive ontology formalized in the Web Ontology Language (OWL 2 DL), a Resource Description Framework (RDF) model for capturing detailed results of manual annotation of pharmacogenomic information in drug product labels, and an RDF conversion of relevant biomedical datasets. Our work goes beyond the state of the art in that it makes both automated reasoning as well as query answering as simple as possible, and the reasoning capabilities go beyond the capabilities of previously described ontologies.",
keywords = "Pharmacogenetics, clinical decision support systems, medical informatics, ontology, pharmacogenomics",
author = "Matthias Samwald and Robert Freimuth and Luciano, {Joanne S.} and Simon Lin and Powers, {Robert L.} and Marshall, {M. Scott} and Adlassnig, {Klaus Peter} and Michel Dumontier and Boyce, {Richard D.}",
note = "Copyright: Copyright 2019 Elsevier B.V., All rights reserved.; 14th World Congress on Medical and Health Informatics, MEDINFO 2013 ; Conference date: 20-08-2013 Through 23-08-2013",
year = "2013",
doi = "10.3233/978-1-61499-289-9-539",
language = "English (US)",
isbn = "9781614992882",
series = "Studies in Health Technology and Informatics",
publisher = "IOS Press",
number = "1-2",
pages = "539--542",
booktitle = "MEDINFO 2013 - Proceedings of the 14th World Congress on Medical and Health Informatics",
edition = "1-2",
}