TY - JOUR
T1 - An informatics research agenda to support precision medicine
T2 - Seven key areas
AU - Tenenbaum, Jessica D.
AU - Avillach, Paul
AU - Benham-Hutchins, Marge
AU - Breitenstein, Matthew K.
AU - Crowgey, Erin L.
AU - Hoffman, Mark A.
AU - Jiang, Xia
AU - Madhavan, Subha
AU - Mattison, John E.
AU - Nagarajan, Radhakrishnan
AU - Ray, Bisakha
AU - Shin, Dmitriy
AU - Visweswaran, Shyam
AU - Zhao, Zhongming
AU - Freimuth, Robert R.
N1 - Publisher Copyright:
© 2016 The Author.
PY - 2016/7
Y1 - 2016/7
N2 - The recent announcement of the Precision Medicine Initiative by President Obama has brought precision medicine (PM) to the forefront for healthcare providers, researchers, regulators, innovators, and funders alike. As technologies continue to evolve and datasets grow in magnitude, a strong computational infrastructure will be essential to realize PM's vision of improved healthcare derived from personal data. In addition, informatics research and innovation affords a tremendous opportunity to drive the science underlying PM. The informatics community must lead the development of technologies and methodologies that will increase the discovery and application of biomedical knowledge through close collaboration between researchers, clinicians, and patients. This perspective highlights seven key areas that are in need of further informatics research and innovation to support the realization of PM.
AB - The recent announcement of the Precision Medicine Initiative by President Obama has brought precision medicine (PM) to the forefront for healthcare providers, researchers, regulators, innovators, and funders alike. As technologies continue to evolve and datasets grow in magnitude, a strong computational infrastructure will be essential to realize PM's vision of improved healthcare derived from personal data. In addition, informatics research and innovation affords a tremendous opportunity to drive the science underlying PM. The informatics community must lead the development of technologies and methodologies that will increase the discovery and application of biomedical knowledge through close collaboration between researchers, clinicians, and patients. This perspective highlights seven key areas that are in need of further informatics research and innovation to support the realization of PM.
KW - Biomarkers
KW - Data sharing
KW - Informatics
KW - Precision medicine
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UR - http://www.scopus.com/inward/citedby.url?scp=84981180095&partnerID=8YFLogxK
U2 - 10.1093/jamia/ocv213
DO - 10.1093/jamia/ocv213
M3 - Article
C2 - 27107452
AN - SCOPUS:84981180095
SN - 1067-5027
VL - 23
SP - 791
EP - 795
JO - Journal of the American Medical Informatics Association
JF - Journal of the American Medical Informatics Association
IS - 4
ER -