An evaluation of the NQF Quality Data Model for representing Electronic Health Record driven phenotyping algorithms.

William K. Thompson, Luke V. Rasmussen, Jennifer A. Pacheco, Peggy L. Peissig, Joshua C. Denny, Abel N. Kho, Aaron Miller, Jyotishman Pathak

Research output: Contribution to journalArticle

22 Scopus citations

Abstract

The development of Electronic Health Record (EHR)-based phenotype selection algorithms is a non-trivial and highly iterative process involving domain experts and informaticians. To make it easier to port algorithms across institutions, it is desirable to represent them using an unambiguous formal specification language. For this purpose we evaluated the recently developed National Quality Forum (NQF) information model designed for EHR-based quality measures: the Quality Data Model (QDM). We selected 9 phenotyping algorithms that had been previously developed as part of the eMERGE consortium and translated them into QDM format. Our study concluded that the QDM contains several core elements that make it a promising format for EHR-driven phenotyping algorithms for clinical research. However, we also found areas in which the QDM could be usefully extended, such as representing information extracted from clinical text, and the ability to handle algorithms that do not consist of Boolean combinations of criteria.

Original languageEnglish (US)
Pages (from-to)911-920
Number of pages10
JournalUnknown Journal
Volume2012
StatePublished - 2012

ASJC Scopus subject areas

  • Medicine(all)

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    Thompson, W. K., Rasmussen, L. V., Pacheco, J. A., Peissig, P. L., Denny, J. C., Kho, A. N., Miller, A., & Pathak, J. (2012). An evaluation of the NQF Quality Data Model for representing Electronic Health Record driven phenotyping algorithms. Unknown Journal, 2012, 911-920.