An Alternative Echocardiographic Method to Estimate Mean Pulmonary Artery Pressure: Diagnostic and Clinical Implications

Javier F. Aduen, Ramon Castello, Marcelo M. Lozano, George N. Hepler, Cesar A. Keller, Francisco Alvarez, Robert E. Safford, Julia E. Crook, Michael G. Heckman, Charles D. Burger

Research output: Contribution to journalArticle

52 Scopus citations


Background: The aim of this study was to evaluated an alternative echocardiographic method to calculate mean pulmonary arterial pressure (MPAP). Methods: One hundred two patients were studied with simultaneous right-heart catheterization (RHC) and echocardiography. MPAP was calculated by adding the right ventricular-right atrial mean systolic gradient to right atrial pressure. Results: The mean difference between MPAP calculated using this method and RHC-derived MPAP was -1.6 mm Hg, less than that of traditional systolic pulmonary arterial pressure (SPAP; -6.4 mm Hg) and MPAP estimated using the pulmonary regurgitation method (-13.9 mm Hg). The median absolute percentage difference of the MPAP calculations relative to RHC was significantly less with this method than with the pulmonary regurgitation method (18% vs 71%; P < .001) and similar to the SPAP method (both 18%; P = .30). Conclusion: MPAP calculated using the proposed method is as accurate as SPAP calculation and less variable than previous methods, thus allowing widespread clinical use.

Original languageEnglish (US)
Pages (from-to)814-819
Number of pages6
JournalJournal of the American Society of Echocardiography
Issue number7
StatePublished - Jul 1 2009



  • Doppler echocardiography
  • Mean pulmonary pressure
  • Pulmonary hypertension

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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