An Alternative Echocardiographic Method to Estimate Mean Pulmonary Artery Pressure: Diagnostic and Clinical Implications

Javier F. Aduen; Ramon Castello; Marcelo M. Lozano; George N. Hepler; Cesar A. Keller; Francisco Alvarez; Robert E. Safford; Julia E. Crook; Michael G. Heckman; Charles D. Burger

doi:10.1016/j.echo.2009.04.007

An Alternative Echocardiographic Method to Estimate Mean Pulmonary Artery Pressure: Diagnostic and Clinical Implications

Javier F. Aduen, Ramon Castello, Marcelo M. Lozano, George N. Hepler, Cesar A. Keller, Francisco Alvarez, Robert E. Safford, Julia E. Crook, Michael G. Heckman, Charles D. Burger

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

Background: The aim of this study was to evaluated an alternative echocardiographic method to calculate mean pulmonary arterial pressure (MPAP). Methods: One hundred two patients were studied with simultaneous right-heart catheterization (RHC) and echocardiography. MPAP was calculated by adding the right ventricular-right atrial mean systolic gradient to right atrial pressure. Results: The mean difference between MPAP calculated using this method and RHC-derived MPAP was -1.6 mm Hg, less than that of traditional systolic pulmonary arterial pressure (SPAP; -6.4 mm Hg) and MPAP estimated using the pulmonary regurgitation method (-13.9 mm Hg). The median absolute percentage difference of the MPAP calculations relative to RHC was significantly less with this method than with the pulmonary regurgitation method (18% vs 71%; P < .001) and similar to the SPAP method (both 18%; P = .30). Conclusion: MPAP calculated using the proposed method is as accurate as SPAP calculation and less variable than previous methods, thus allowing widespread clinical use.

Original language	English (US)
Pages (from-to)	814-819
Number of pages	6
Journal	Journal of the American Society of Echocardiography
Volume	22
Issue number	7
DOIs	https://doi.org/10.1016/j.echo.2009.04.007
State	Published - Jul 2009

Keywords

Doppler echocardiography
Mean pulmonary pressure
Pulmonary hypertension

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

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10.1016/j.echo.2009.04.007

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Aduen, J. F., Castello, R., Lozano, M. M., Hepler, G. N., Keller, C. A., Alvarez, F., Safford, R. E., Crook, J. E., Heckman, M. G., & Burger, C. D. (2009). An Alternative Echocardiographic Method to Estimate Mean Pulmonary Artery Pressure: Diagnostic and Clinical Implications. Journal of the American Society of Echocardiography, 22(7), 814-819. https://doi.org/10.1016/j.echo.2009.04.007

Aduen, JF, Castello, R, Lozano, MM, Hepler, GN, Keller, CA, Alvarez, F, Safford, RE, Crook, JE, Heckman, MG & Burger, CD 2009, 'An Alternative Echocardiographic Method to Estimate Mean Pulmonary Artery Pressure: Diagnostic and Clinical Implications', Journal of the American Society of Echocardiography, vol. 22, no. 7, pp. 814-819. https://doi.org/10.1016/j.echo.2009.04.007

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abstract = "Background: The aim of this study was to evaluated an alternative echocardiographic method to calculate mean pulmonary arterial pressure (MPAP). Methods: One hundred two patients were studied with simultaneous right-heart catheterization (RHC) and echocardiography. MPAP was calculated by adding the right ventricular-right atrial mean systolic gradient to right atrial pressure. Results: The mean difference between MPAP calculated using this method and RHC-derived MPAP was -1.6 mm Hg, less than that of traditional systolic pulmonary arterial pressure (SPAP; -6.4 mm Hg) and MPAP estimated using the pulmonary regurgitation method (-13.9 mm Hg). The median absolute percentage difference of the MPAP calculations relative to RHC was significantly less with this method than with the pulmonary regurgitation method (18% vs 71%; P < .001) and similar to the SPAP method (both 18%; P = .30). Conclusion: MPAP calculated using the proposed method is as accurate as SPAP calculation and less variable than previous methods, thus allowing widespread clinical use.",

keywords = "Doppler echocardiography, Mean pulmonary pressure, Pulmonary hypertension",

author = "Aduen, {Javier F.} and Ramon Castello and Lozano, {Marcelo M.} and Hepler, {George N.} and Keller, {Cesar A.} and Francisco Alvarez and Safford, {Robert E.} and Crook, {Julia E.} and Heckman, {Michael G.} and Burger, {Charles D.}",

year = "2009",

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doi = "10.1016/j.echo.2009.04.007",

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T1 - An Alternative Echocardiographic Method to Estimate Mean Pulmonary Artery Pressure

T2 - Diagnostic and Clinical Implications

AU - Aduen, Javier F.

AU - Castello, Ramon

AU - Lozano, Marcelo M.

AU - Hepler, George N.

AU - Keller, Cesar A.

AU - Alvarez, Francisco

AU - Safford, Robert E.

AU - Crook, Julia E.

AU - Heckman, Michael G.

AU - Burger, Charles D.

PY - 2009/7

Y1 - 2009/7

N2 - Background: The aim of this study was to evaluated an alternative echocardiographic method to calculate mean pulmonary arterial pressure (MPAP). Methods: One hundred two patients were studied with simultaneous right-heart catheterization (RHC) and echocardiography. MPAP was calculated by adding the right ventricular-right atrial mean systolic gradient to right atrial pressure. Results: The mean difference between MPAP calculated using this method and RHC-derived MPAP was -1.6 mm Hg, less than that of traditional systolic pulmonary arterial pressure (SPAP; -6.4 mm Hg) and MPAP estimated using the pulmonary regurgitation method (-13.9 mm Hg). The median absolute percentage difference of the MPAP calculations relative to RHC was significantly less with this method than with the pulmonary regurgitation method (18% vs 71%; P < .001) and similar to the SPAP method (both 18%; P = .30). Conclusion: MPAP calculated using the proposed method is as accurate as SPAP calculation and less variable than previous methods, thus allowing widespread clinical use.

AB - Background: The aim of this study was to evaluated an alternative echocardiographic method to calculate mean pulmonary arterial pressure (MPAP). Methods: One hundred two patients were studied with simultaneous right-heart catheterization (RHC) and echocardiography. MPAP was calculated by adding the right ventricular-right atrial mean systolic gradient to right atrial pressure. Results: The mean difference between MPAP calculated using this method and RHC-derived MPAP was -1.6 mm Hg, less than that of traditional systolic pulmonary arterial pressure (SPAP; -6.4 mm Hg) and MPAP estimated using the pulmonary regurgitation method (-13.9 mm Hg). The median absolute percentage difference of the MPAP calculations relative to RHC was significantly less with this method than with the pulmonary regurgitation method (18% vs 71%; P < .001) and similar to the SPAP method (both 18%; P = .30). Conclusion: MPAP calculated using the proposed method is as accurate as SPAP calculation and less variable than previous methods, thus allowing widespread clinical use.

KW - Doppler echocardiography

KW - Mean pulmonary pressure

KW - Pulmonary hypertension

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An Alternative Echocardiographic Method to Estimate Mean Pulmonary Artery Pressure: Diagnostic and Clinical Implications

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