Amyloidosis

Research output: Contribution to journalArticle

133 Citations (Scopus)

Abstract

Amyloidosis is considered rare but has an incidence similar to that of Hodgkin's disease and chronic granulocytic leukemia. The diagnosis should be considered in any patient with unexplained nephrotic-range proteinuria, heart failure, peripheral neruopathy, or hepatomegaly. If a monoclonal protein is found in a patient with any of these clinical presentations, a biopsy should be performed and the specimen stained with Congo red. The simplest source of diagnostic material is subcutaneous fat tissue. Treatment usually consists of chemotherapy, which may be oral and low dose or high dose with stem cell rescue.

Original languageEnglish (US)
Pages (from-to)1211-1233
Number of pages23
JournalHematology/Oncology Clinics of North America
Volume13
Issue number6
StatePublished - 1999

Fingerprint

Amyloidosis
Congo Red
Hepatomegaly
Subcutaneous Fat
Subcutaneous Tissue
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Hodgkin Disease
Proteinuria
Stem Cells
Heart Failure
Biopsy
Drug Therapy
Incidence
Proteins
Therapeutics

ASJC Scopus subject areas

  • Hematology
  • Oncology

Cite this

Amyloidosis. / Gertz, Morie; Lacy, Martha; Dispenzieri, Angela.

In: Hematology/Oncology Clinics of North America, Vol. 13, No. 6, 1999, p. 1211-1233.

Research output: Contribution to journalArticle

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