Amyloid β vaccination

Reduced plaques and improved cognition

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Studies in three different transgenic mouse models suggest that the amyloid β-protein contributes to memory loss in Alzheimer disease. Immunization with an amyloid β-peptide fragment reduces learning memory impairments in mice this approach may eventually be used to prevent and/or treat this disease in people.

Original languageEnglish (US)
Pages (from-to)18-19
Number of pages2
JournalNature Medicine
Volume7
Issue number1
DOIs
StatePublished - 2001

Fingerprint

Amyloidogenic Proteins
Peptide Fragments
Memory Disorders
Amyloid
Cognition
Transgenic Mice
Immunization
Alzheimer Disease
Vaccination
Learning
Data storage equipment

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Amyloid β vaccination : Reduced plaques and improved cognition. / Younkin, Steven G.

In: Nature Medicine, Vol. 7, No. 1, 2001, p. 18-19.

Research output: Contribution to journalArticle

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