TY - JOUR
T1 - Amiodarone Pulmonary Toxicity
T2 - Report of Two Cases Associated With Rapidly Progressive Fatal Adult Respiratory Distress Syndrome After Pulmonary Angiography
AU - WOOD, DOUGLAS L.
AU - OSBORN, MICHAEL J.
AU - ROOKE, JULIANNE
AU - HOLMES, DAVID R.
PY - 1985
Y1 - 1985
N2 - Use of amiodarone, an investigational antidysrhythmic agent, has been associated with cases of pulmonary toxicity. The mechanism of amiodarone pulmonary toxicity is unknown, and recommendations for the assessment and treatment of patients with this condition continue to evolve. In two patients with clinically diagnosed amiodarone pulmonary toxicity, a rapidly progressive and fatal adult respiratory distress syndrome developed after pulmonary angiography. Physicians should be aware of the potential for serious complications of pulmonary angiography in patients with presumed or clinically diagnosed amiodarone toxicity.
AB - Use of amiodarone, an investigational antidysrhythmic agent, has been associated with cases of pulmonary toxicity. The mechanism of amiodarone pulmonary toxicity is unknown, and recommendations for the assessment and treatment of patients with this condition continue to evolve. In two patients with clinically diagnosed amiodarone pulmonary toxicity, a rapidly progressive and fatal adult respiratory distress syndrome developed after pulmonary angiography. Physicians should be aware of the potential for serious complications of pulmonary angiography in patients with presumed or clinically diagnosed amiodarone toxicity.
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U2 - 10.1016/S0025-6196(12)60983-5
DO - 10.1016/S0025-6196(12)60983-5
M3 - Article
C2 - 4021550
AN - SCOPUS:0022181705
SN - 0025-6196
VL - 60
SP - 601
EP - 603
JO - Mayo Clinic proceedings
JF - Mayo Clinic proceedings
IS - 9
ER -