TY - JOUR
T1 - American Society of Transplant Surgeons recommendations on best practices in donation after circulatory death organ procurement
AU - American Society of Transplant Surgeons Scientific Studies Committee
AU - Croome, Kristopher
AU - Barbas, Andrew S.
AU - Whitson, Bryan
AU - Zarrinpar, Ali
AU - Taner, Timucin
AU - Lo, Denise
AU - MacConmara, Malcolm
AU - Kim, Jim
AU - Kennealey, Peter T.
AU - Bromberg, Jonathan S.
AU - Washburn, Kenneth
AU - Agopian, Vatche G.
AU - Stegall, Mark
AU - Quintini, Cristiano
N1 - Publisher Copyright:
Copyright © 2022 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved.
PY - 2023/2/1
Y1 - 2023/2/1
N2 - The American Society of Transplant Surgeons supports efforts to increase the number of organs that are critically needed for patients desperately awaiting transplantation. In the United States, transplantation using organs procured from donation after circulatory death (DCD) donors has continued to increase in number. Despite these increases, substantial variability in the utilization and practices of DCD transplantation still exists. To improve DCD organ utilization, it is important to create a set of best practices for DCD recovery. The following recommendations aim to provide guidance on contemporary issues surrounding DCD organ procurement in the United States. A work group was composed of members of the American Society of Transplant Surgeon Scientific Studies Committee and the Thoracic Organ Transplantation Committee. The following topics were identified by the group either as controversial or lacking standardization: prewithdrawal preparation, definition of donor warm ischemia time, DCD surgical technique, combined thoracic and abdominal procurements, and normothermic regional perfusion. The proposed recommendations were classified on the basis of the grade of available evidence and the strength of the recommendation. This information should be valuable for transplant programs as well as for organ procurement organizations and donor hospitals as they develop robust DCD donor procurement protocols.
AB - The American Society of Transplant Surgeons supports efforts to increase the number of organs that are critically needed for patients desperately awaiting transplantation. In the United States, transplantation using organs procured from donation after circulatory death (DCD) donors has continued to increase in number. Despite these increases, substantial variability in the utilization and practices of DCD transplantation still exists. To improve DCD organ utilization, it is important to create a set of best practices for DCD recovery. The following recommendations aim to provide guidance on contemporary issues surrounding DCD organ procurement in the United States. A work group was composed of members of the American Society of Transplant Surgeon Scientific Studies Committee and the Thoracic Organ Transplantation Committee. The following topics were identified by the group either as controversial or lacking standardization: prewithdrawal preparation, definition of donor warm ischemia time, DCD surgical technique, combined thoracic and abdominal procurements, and normothermic regional perfusion. The proposed recommendations were classified on the basis of the grade of available evidence and the strength of the recommendation. This information should be valuable for transplant programs as well as for organ procurement organizations and donor hospitals as they develop robust DCD donor procurement protocols.
KW - clinical research/practice
KW - donors and donation: deceased
KW - donors and donation: donation after circulatory death (DCD)
KW - normothermic regional perfusion (NRP)
KW - organ procurement
KW - organ procurement and allocation
KW - solid organ transplantation
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U2 - 10.1016/j.ajt.2022.10.009
DO - 10.1016/j.ajt.2022.10.009
M3 - Review article
C2 - 36695685
AN - SCOPUS:85148479318
SN - 1600-6135
VL - 23
SP - 171
EP - 179
JO - American Journal of Transplantation
JF - American Journal of Transplantation
IS - 2
ER -