TY - JOUR
T1 - Amblyopia in childhood eyelid ptosis
AU - Griepentrog, Gregory J.
AU - Diehl, Nancy
AU - Mohney, Brian G.
N1 - Funding Information:
All authors have completed and submitted the ICMJE form for disclosure of potential conflicts of interest and none were reported. Publication of this article was supported in part by the Rochester Epidemiology Project (grant no. R01-AG034676 from the National Institute of Arthritis, Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, Maryland); and by an unrestricted grant from Research to Prevent Blindness Inc, New York, New York, at both the Mayo Clinic and Medical College of Wisconsin. Involved in Design of study (G.J.G., B.G.M.); Conduct of study (G.J.G., N.D., B.G.M.); Analysis and interpretation of data (G.J.G., N.D., B.G.M.); Drafting and revising article (G.J.G., N.D., B.G.M.); and Final approval of manuscript (G.J.G., N.D., B.G.M.).
PY - 2013/6
Y1 - 2013/6
N2 - Purpose: To report the prevalence and causes of amblyopia among children with ptosis diagnosed in a well-defined population over a 40-year period. Design: Retrospective, population-based cohort study. Methods: We retrospectively reviewed the charts of 107 patients younger than 19 years for the prevalence and causes of amblyopia who were diagnosed with childhood ptosis and were residents of Olmsted County, Minnesota, from January 1, 1965, through December 31, 2004. Results: Amblyopia was diagnosed in 16 (14.9%) of the 107 patients with childhood ptosis. Fourteen (14.6%) of 96 patients diagnosed with a congenital form of ptosis demonstrated amblyopia. Twelve (14.8%) of the 81 patients diagnosed with simple congenital ptosis had amblyopia, 7 (8.6%) cases of which solely were the result of eyelid occlusion of the visual axis. The causes of amblyopia in the remaining 5 patients were significant refractive error in 3 patients and strabismus in 2 patients. Conclusions: Amblyopia occurred in 1 in 7 children diagnosed with ptosis in this population-based cohort. In approximately half of those with amblyopia, or less than 10% of all patients, the disease solely was the result of eyelid occlusion of the visual axis.
AB - Purpose: To report the prevalence and causes of amblyopia among children with ptosis diagnosed in a well-defined population over a 40-year period. Design: Retrospective, population-based cohort study. Methods: We retrospectively reviewed the charts of 107 patients younger than 19 years for the prevalence and causes of amblyopia who were diagnosed with childhood ptosis and were residents of Olmsted County, Minnesota, from January 1, 1965, through December 31, 2004. Results: Amblyopia was diagnosed in 16 (14.9%) of the 107 patients with childhood ptosis. Fourteen (14.6%) of 96 patients diagnosed with a congenital form of ptosis demonstrated amblyopia. Twelve (14.8%) of the 81 patients diagnosed with simple congenital ptosis had amblyopia, 7 (8.6%) cases of which solely were the result of eyelid occlusion of the visual axis. The causes of amblyopia in the remaining 5 patients were significant refractive error in 3 patients and strabismus in 2 patients. Conclusions: Amblyopia occurred in 1 in 7 children diagnosed with ptosis in this population-based cohort. In approximately half of those with amblyopia, or less than 10% of all patients, the disease solely was the result of eyelid occlusion of the visual axis.
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U2 - 10.1016/j.ajo.2012.12.015
DO - 10.1016/j.ajo.2012.12.015
M3 - Article
C2 - 23428108
AN - SCOPUS:84877740851
VL - 155
SP - 1125-1128.e1
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
SN - 0002-9394
IS - 6
ER -