Alzheimer's disease presenting as corticobasal syndrome

Pratap Chand, Jordan Grafman, Dennis Dickson, Keisuke Ishizawa, Irene Litvan

Research output: Contribution to journalArticle

42 Scopus citations

Abstract

A 60-year-old man presented with slowly progressive left hemi-Parkinsonism, left hand apraxia, myoclonus, dystonia, visuospatial. disturbances, and alien limb phenomenon, resembling corticobasal syndrome. Eight years later, neuropathology revealed features of Alzheimer's disease, with asymmetrical (right more than left) cortical tau burden with image analysis. The videotaped clinical features, neuropsychological aspects, and neuropathological correlates are presented and discussed.

Original languageEnglish (US)
Pages (from-to)2018-2022
Number of pages5
JournalMovement Disorders
Volume21
Issue number11
DOIs
StatePublished - Nov 1 2006

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Keywords

  • Alien limb phenomenon
  • Alzheimer's disease
  • Corticobasal degeneration
  • Corticobasal syndrome
  • Myoclonus
  • Neuropathology

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Chand, P., Grafman, J., Dickson, D., Ishizawa, K., & Litvan, I. (2006). Alzheimer's disease presenting as corticobasal syndrome. Movement Disorders, 21(11), 2018-2022. https://doi.org/10.1002/mds.21055