Alveolar Soft-Part Sarcoma Responsive to Intensive Chemotherapy

H. James Nickerson, Teresa Silberman, F. Stig Jacobsen, Bruce R. Krawisz, Hope S. Maki, Carola A.S. Arndt

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Alveolar soft-part sarcoma (ASPS) is a very rare malignant tumor, usually of the extremities, and is seen most often in adolescents and young adults. Surgical excision of the primary and pulmonary metastases has resulted in prolonged survival in some patients, but adjuvant radiation and/or chemotherapy are generally thought to be ineffective. The authors describe a 13-year-old patient with ASPS of an extremity who presented with multiple bilateral pulmonary metastases at diagnosis. Following intensive multiagent chemotherapy, pulmonary metastases showed in vivo evidence of tumor death. The patient has remained disease-free for 10 years following treatment.

Original languageEnglish (US)
Pages (from-to)233-235
Number of pages3
JournalJournal of Pediatric Hematology/Oncology
Volume26
Issue number4
DOIs
StatePublished - Apr 1 2004

Keywords

  • Alveolar soft-part sarcoma
  • Chemotherapy
  • Etoposide
  • Ifosfamide
  • Pulmonary metastases

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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