TY - JOUR
T1 - Altitude-related illnesses
AU - Klocke, David L.
AU - Decker, Wyatt W.
AU - Stepanek, Jan
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1998
Y1 - 1998
N2 - Altitude-related illnesses are a frequent cause of morbidity and occasional mortality in travelers to high altitudes in the United States and throughout the world. The primary altitude illnesses are acute mountain sickness, high-altitude pulmonary edema, and high-altitude cerebral edema. The pathogenesis of these syndromes remains unclear despite considerable research. Altitude also has potential deleterious effects on common medical conditions including coronary artery disease, pulmonary disease, hemoglobinopathies, and pregnancy. Most of these problems are primarily preventable with appropriate information before travel. Education should include information about rate of ascent, diet, alcohol intake, physical activity, and preventive medications, including acetazolamide, nifedipine, and dexamethasone in selected circumstances.
AB - Altitude-related illnesses are a frequent cause of morbidity and occasional mortality in travelers to high altitudes in the United States and throughout the world. The primary altitude illnesses are acute mountain sickness, high-altitude pulmonary edema, and high-altitude cerebral edema. The pathogenesis of these syndromes remains unclear despite considerable research. Altitude also has potential deleterious effects on common medical conditions including coronary artery disease, pulmonary disease, hemoglobinopathies, and pregnancy. Most of these problems are primarily preventable with appropriate information before travel. Education should include information about rate of ascent, diet, alcohol intake, physical activity, and preventive medications, including acetazolamide, nifedipine, and dexamethasone in selected circumstances.
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U2 - 10.4065/73.10.988
DO - 10.4065/73.10.988
M3 - Review article
C2 - 9787751
AN - SCOPUS:0031695504
SN - 0025-6196
VL - 73
SP - 988
EP - 993
JO - Mayo Clinic proceedings
JF - Mayo Clinic proceedings
IS - 10
ER -