Altered median nerve deformation and transverse displacement during wrist movement in patients with carpal tunnel syndrome

Yuexiang Wang, Anika Filius, Chunfeng D Zhao, Sandra M. Passe, Andrew R. Thoreson, Kai Nan An, Peter C Amadio

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Rationale and Objectives: Carpal tunnel syndrome (CTS) is the most common peripheral nerve entrapment syndrome. Strong pinch or grip with wrist flexion has been considered a risk factor for CTS. Studying median nerve displacement during wrist movements may provide useful information about median nerve kinematic changes in patients with CTS. The purpose of this study was to evaluate the deformability and mobility of the median nerve in patients with CTS compared to healthy subjects. Materials and Methods: Dynamic ultrasound images were obtained in 20 affected wrists of 13 patients with CTS. Results were compared to complementary data obtained from both wrists of 10 healthy subjects reported in a previous study. Shape and position of initial and final median nerve were measured and analyzed for six defined wrist movements. The deformation ratios for each movement were defined as the median nerve area, perimeter, and circularity of the final position normalized by respective values assessed in the initial position. The median nerve displacement vector and magnitude were also calculated. Results: The deformation ratio for circularity was significantly less in patients with CTS compared to healthy subjects during wrist flexion (P<.05). The mean vector of median nerve displacement during wrist flexion was significantly different between patients with CTS and healthy subjects (P<.05). The displacement magnitude of the median nerve was found to be less in patients with CTS compared to healthy subjects during most movements, with the exception of wrist extension with fingers extended. Conclusions: Patients with CTS differ from normal subjects with regard to mobility and deformability of the median nerve.

Original languageEnglish (US)
Pages (from-to)472-480
Number of pages9
JournalAcademic Radiology
Volume21
Issue number4
DOIs
StatePublished - Apr 2014

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Carpal Tunnel Syndrome
Median Nerve
Wrist
Healthy Volunteers
Nerve Compression Syndromes
Hand Strength
Peripheral Nerves
Biomechanical Phenomena
Fingers

Keywords

  • Carpal tunnel syndrome
  • Median nerve
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Altered median nerve deformation and transverse displacement during wrist movement in patients with carpal tunnel syndrome. / Wang, Yuexiang; Filius, Anika; Zhao, Chunfeng D; Passe, Sandra M.; Thoreson, Andrew R.; An, Kai Nan; Amadio, Peter C.

In: Academic Radiology, Vol. 21, No. 4, 04.2014, p. 472-480.

Research output: Contribution to journalArticle

Wang, Yuexiang ; Filius, Anika ; Zhao, Chunfeng D ; Passe, Sandra M. ; Thoreson, Andrew R. ; An, Kai Nan ; Amadio, Peter C. / Altered median nerve deformation and transverse displacement during wrist movement in patients with carpal tunnel syndrome. In: Academic Radiology. 2014 ; Vol. 21, No. 4. pp. 472-480.
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