Alleviation of cytotoxic therapy-induced normal tissue damage

Charles Lawrence Loprinzi, R. L. Foote, J. Michalak

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Cytotoxic chemotherapy and radiation therapy damage normal body tissues, resulting in stomatitis, conjunctivitis, esophagitis, proctitis, and dermatitis. Pursuant to this, the North Central Cancer Treatment Group has developed a series of clinical trials designed to study antidotes for these pathologic processes. These trials have demonstrated clinically helpful therapies (eg, oral cryotherapy for decreasing mucositis induced by 5- fluorouracil) and also have demonstrated lack of benefit for other proposed treatments. Results from several ongoing clinical trials should become available in the near future.

Original languageEnglish (US)
Pages (from-to)95-97
Number of pages3
JournalSeminars in Oncology
Volume22
Issue numberSUPPL. 3
StatePublished - 1995

Fingerprint

Clinical Trials
Proctitis
Antidotes
Stomatitis
Mucositis
Cryotherapy
Conjunctivitis
Esophagitis
Dermatitis
Pathologic Processes
Fluorouracil
Radiotherapy
Therapeutics
Drug Therapy
Neoplasms

ASJC Scopus subject areas

  • Oncology

Cite this

Loprinzi, C. L., Foote, R. L., & Michalak, J. (1995). Alleviation of cytotoxic therapy-induced normal tissue damage. Seminars in Oncology, 22(SUPPL. 3), 95-97.

Alleviation of cytotoxic therapy-induced normal tissue damage. / Loprinzi, Charles Lawrence; Foote, R. L.; Michalak, J.

In: Seminars in Oncology, Vol. 22, No. SUPPL. 3, 1995, p. 95-97.

Research output: Contribution to journalArticle

Loprinzi, CL, Foote, RL & Michalak, J 1995, 'Alleviation of cytotoxic therapy-induced normal tissue damage', Seminars in Oncology, vol. 22, no. SUPPL. 3, pp. 95-97.
Loprinzi, Charles Lawrence ; Foote, R. L. ; Michalak, J. / Alleviation of cytotoxic therapy-induced normal tissue damage. In: Seminars in Oncology. 1995 ; Vol. 22, No. SUPPL. 3. pp. 95-97.
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