Alkaloids from Toddalia aculeata

Subhash C. Jain; Mukesh K. Pandey; Ravi K. Upadhyay; Rohtash Kumar; Geeta Hundal; Maninder S. Hundal

doi:10.1016/j.phytochem.2006.03.012

Alkaloids from Toddalia aculeata

Subhash C. Jain, Mukesh K. Pandey, Ravi K. Upadhyay, Rohtash Kumar, Geeta Hundal, Maninder S. Hundal

Radiology

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Two alkaloids N-methyl-4-hydroxy-7-methoxy-3-(2,3-epoxy-3-methylbutyl)-1H-quinolin-2-one (1) and 3-(2,3-dihydroxy-3-methylbutyl)-4,7-dimethoxy-1-methyl-1H-quinolin-2-one (2a) have been isolated from CH₂Cl₂:methanol (1:1) and methanol extracts of leaves and stems of Toddalia aculeata. Their structures along with that of 15 other compounds, of which three are isolated for the first time from genus Toddalia, were established by their detailed spectral studies including 2D NMR viz. ¹H-¹H COSY, ¹H-¹³C COSY, and HMBC.

Original language	English (US)
Pages (from-to)	1005-1010
Number of pages	6
Journal	Phytochemistry
Volume	67
Issue number	10
DOIs	https://doi.org/10.1016/j.phytochem.2006.03.012
State	Published - May 2006

Keywords

3-(2,3-Dihydroxy-3-methylbutyl)-4,7-dimethoxy-1-methyl-1H-quinolin-2-one
Alkaloids
N-methyl-4-hydroxy-7-methoxy-3-(2,3-epoxy-3-methylbutyl)-1H-quinolin-2-one
Toddalia aculeata

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Plant Science
Horticulture

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10.1016/j.phytochem.2006.03.012

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title = "Alkaloids from Toddalia aculeata",

abstract = "Two alkaloids N-methyl-4-hydroxy-7-methoxy-3-(2,3-epoxy-3-methylbutyl)-1H-quinolin-2-one (1) and 3-(2,3-dihydroxy-3-methylbutyl)-4,7-dimethoxy-1-methyl-1H-quinolin-2-one (2a) have been isolated from CH2Cl2:methanol (1:1) and methanol extracts of leaves and stems of Toddalia aculeata. Their structures along with that of 15 other compounds, of which three are isolated for the first time from genus Toddalia, were established by their detailed spectral studies including 2D NMR viz. 1H-1H COSY, 1H-13C COSY, and HMBC.",

keywords = "3-(2,3-Dihydroxy-3-methylbutyl)-4,7-dimethoxy-1-methyl-1H-quinolin-2-one, Alkaloids, N-methyl-4-hydroxy-7-methoxy-3-(2,3-epoxy-3-methylbutyl)-1H-quinolin-2-one, Toddalia aculeata",

author = "Jain, {Subhash C.} and Pandey, {Mukesh K.} and Upadhyay, {Ravi K.} and Rohtash Kumar and Geeta Hundal and Hundal, {Maninder S.}",

note = "Funding Information: We thank DANIDA (Danish International Development Agency) for financial assistance. ",

year = "2006",

month = may,

doi = "10.1016/j.phytochem.2006.03.012",

language = "English (US)",

volume = "67",

pages = "1005--1010",

journal = "Phytochemistry",

issn = "0031-9422",

publisher = "Elsevier Limited",

number = "10",

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TY - JOUR

T1 - Alkaloids from Toddalia aculeata

AU - Jain, Subhash C.

AU - Pandey, Mukesh K.

AU - Upadhyay, Ravi K.

AU - Kumar, Rohtash

AU - Hundal, Geeta

AU - Hundal, Maninder S.

N1 - Funding Information: We thank DANIDA (Danish International Development Agency) for financial assistance.

PY - 2006/5

Y1 - 2006/5

N2 - Two alkaloids N-methyl-4-hydroxy-7-methoxy-3-(2,3-epoxy-3-methylbutyl)-1H-quinolin-2-one (1) and 3-(2,3-dihydroxy-3-methylbutyl)-4,7-dimethoxy-1-methyl-1H-quinolin-2-one (2a) have been isolated from CH2Cl2:methanol (1:1) and methanol extracts of leaves and stems of Toddalia aculeata. Their structures along with that of 15 other compounds, of which three are isolated for the first time from genus Toddalia, were established by their detailed spectral studies including 2D NMR viz. 1H-1H COSY, 1H-13C COSY, and HMBC.

AB - Two alkaloids N-methyl-4-hydroxy-7-methoxy-3-(2,3-epoxy-3-methylbutyl)-1H-quinolin-2-one (1) and 3-(2,3-dihydroxy-3-methylbutyl)-4,7-dimethoxy-1-methyl-1H-quinolin-2-one (2a) have been isolated from CH2Cl2:methanol (1:1) and methanol extracts of leaves and stems of Toddalia aculeata. Their structures along with that of 15 other compounds, of which three are isolated for the first time from genus Toddalia, were established by their detailed spectral studies including 2D NMR viz. 1H-1H COSY, 1H-13C COSY, and HMBC.

KW - 3-(2,3-Dihydroxy-3-methylbutyl)-4,7-dimethoxy-1-methyl-1H-quinolin-2-one

KW - Alkaloids

KW - N-methyl-4-hydroxy-7-methoxy-3-(2,3-epoxy-3-methylbutyl)-1H-quinolin-2-one

KW - Toddalia aculeata

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U2 - 10.1016/j.phytochem.2006.03.012

DO - 10.1016/j.phytochem.2006.03.012

M3 - Article

C2 - 16647728

AN - SCOPUS:33646798395

SN - 0031-9422

VL - 67

SP - 1005

EP - 1010

JO - Phytochemistry

JF - Phytochemistry

IS - 10

ER -

Alkaloids from Toddalia aculeata

Abstract

Keywords

ASJC Scopus subject areas

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