Aldosterone antagonism for HFpEF

Barry A. Borlaug

doi:10.1038/nrcardio.2013.51

Aldosterone antagonism for HFpEF

Barry A. Borlaug

Cardiovascular Medicine

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

No therapy has been proven to reduce morbidity and mortality in patients with heart failure and preserved ejection fraction (HFpEF). Owing to the deleterious cardiovascular effects of aldosterone, mineralocorticoid antagonists hold promise to treat this disorder. The Aldo-DHF trial provides valuable insights into the effects of these agents in HFpEF.

Original language	English (US)
Pages (from-to)	244-246
Number of pages	3
Journal	Nature Reviews Cardiology
Volume	10
Issue number	5
DOIs	https://doi.org/10.1038/nrcardio.2013.51
State	Published - May 1 2013

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1038/nrcardio.2013.51

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title = "Aldosterone antagonism for HFpEF",

abstract = "No therapy has been proven to reduce morbidity and mortality in patients with heart failure and preserved ejection fraction (HFpEF). Owing to the deleterious cardiovascular effects of aldosterone, mineralocorticoid antagonists hold promise to treat this disorder. The Aldo-DHF trial provides valuable insights into the effects of these agents in HFpEF.",

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AB - No therapy has been proven to reduce morbidity and mortality in patients with heart failure and preserved ejection fraction (HFpEF). Owing to the deleterious cardiovascular effects of aldosterone, mineralocorticoid antagonists hold promise to treat this disorder. The Aldo-DHF trial provides valuable insights into the effects of these agents in HFpEF.

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Aldosterone antagonism for HFpEF

Abstract

ASJC Scopus subject areas

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