Alcohol Craving Predicts Relapse After Residential Addiction Treatment

Matthew E. Stohs, Terry D. Schneekloth, Jennifer R. Geske, Joanna M Biernacka, Victor M Karpyak

Research output: Contribution to journalArticle

Abstract

AIMS: Replicate the previously reported association of elevated alcohol craving, measured by Penn Alcohol Craving Scale (PACS) during residential treatment, with post-treatment relapse and explore whether elevated craving scores 3 months post-treatment are also associated with subsequent relapse. METHODS: Alcohol craving was assessed with the PACS on admission and at several time points post-treatment in 190 subjects with DSM-IV diagnosis of alcohol dependence admitted to residential treatment. Data about relapse to any drinking (primary outcome measure) was collected at 3, 6, 9 and 12 months after treatment. Cox regression models were used to determine whether PACS scores were associated with relapse. Statistical models were adjusted for meaningful demographic and clinical covariates. RESULTS: Follow-up data was available for 149/190 (78%) of subjects. Elevated PACS scores at discharge were associated with increased relapse risk within the first 3 and 12 months after discharge (P = 0.032 and P = 0.045, respectively). Elevated PACS scores at 3 months were associated with increased risk of subsequent relapse within 12 months after treatment in contacted subjects (P = 0.034) and in the intent-to-treat analysis (P = 0.0001). CONCLUSIONS: Our findings indicate strong association of post-treatment relapse with elevated alcohol craving measured at treatment completion and at 3 months after treatment and justify the use of this measure to guide relapse-prevention efforts.

Original languageEnglish (US)
Pages (from-to)167-172
Number of pages6
JournalAlcohol and alcoholism (Oxford, Oxfordshire)
Volume54
Issue number2
DOIs
StatePublished - Mar 1 2019

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Residential Treatment
Alcohols
Recurrence
Therapeutics
Craving
Statistical Models
Secondary Prevention
Proportional Hazards Models
Diagnostic and Statistical Manual of Mental Disorders
Alcoholism
Drinking
Demography
Outcome Assessment (Health Care)

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Toxicology
  • Psychiatry and Mental health

Cite this

Alcohol Craving Predicts Relapse After Residential Addiction Treatment. / Stohs, Matthew E.; Schneekloth, Terry D.; Geske, Jennifer R.; Biernacka, Joanna M; Karpyak, Victor M.

In: Alcohol and alcoholism (Oxford, Oxfordshire), Vol. 54, No. 2, 01.03.2019, p. 167-172.

Research output: Contribution to journalArticle

Stohs, Matthew E. ; Schneekloth, Terry D. ; Geske, Jennifer R. ; Biernacka, Joanna M ; Karpyak, Victor M. / Alcohol Craving Predicts Relapse After Residential Addiction Treatment. In: Alcohol and alcoholism (Oxford, Oxfordshire). 2019 ; Vol. 54, No. 2. pp. 167-172.
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