Akt inhibitor MK2206 selectively targets CLL B-cell receptor induced cytokines, mobilizes lymphocytes and synergizes with bendamustine to induce CLL apoptosis

Wei Ding, Tait D. Shanafelt, Connie E. Lesnick, Charles Erlichman, Jose F. Leis, Charla Secreto, Traci R. Sassoon, Timothy G. Call, Deborah A. Bowen, Michael Conte, Shaji Kumar, Neil E. Kay

Research output: Contribution to journalLetter

14 Scopus citations
Original languageEnglish (US)
Pages (from-to)146-150
Number of pages5
JournalBritish journal of haematology
Volume164
Issue number1
DOIs
StatePublished - Jan 2014

Keywords

  • Akt
  • B cell receptor
  • Chronic lymphocytic leukaemia
  • Cytokine

ASJC Scopus subject areas

  • Hematology

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