Age of fracture and clinical outcomes of percutaneous vertebroplasty

Timothy J Kaufmann, M. E. Jensen, P. A. Schweickert, W. F. Marx, David F Kallmes

Research output: Contribution to journalArticle

149 Citations (Scopus)

Abstract

BACKGROUND AND PURPOSE: The patient populations that are most likely to benefit from percutaneous vertebroplasty (PVP) are uncertain. Our purpose was to evaluate the effect of the age of vertebral compression fracture (VCF) on clinical improvement after PVP. METHODS: We performed a retrospective review of charts of patients who had undergone PVP for painful osteoporotic VCFs at our institution. The preprocedural and postprocedural outcome measurements of pain, mobility, and analgesic use were compared for 80 treatment sessions in 75 patients (122 total vertebrae treated). We assessed the association between the duration of pain before PVP and postprocedural outcomes by using multivariable analysis. RESULTS: Age of fracture at time of PVP was not independently associated with postprocedural pain or activity. Increasing age of fracture was independently associated with slightly greater postprocedural analgesic requirement, at least for patients who required narcotics at baseline before PVP. Greater preprocedural analgesic requirement was independently associated with greater postprocedural analgesic requirement. Reduced preprocedural mobility was independently associated with reduced postprocedural mobility. CONCLUSION: PVP is a highly efficacious therapy for relief of pain and improvement in mobility, regardless of fracture age. PVP also is efficacious in reducing analgesic requirement, although this effect may be slightly blunted in patients who require narcotics before the procedure and in those who have older fractures.

Original languageEnglish (US)
Pages (from-to)1860-1863
Number of pages4
JournalAmerican Journal of Neuroradiology
Volume22
Issue number10
StatePublished - 2001
Externally publishedYes

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Vertebroplasty
Analgesics
Narcotics
Pain
Compression Fractures
Pain Measurement
Spine

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Age of fracture and clinical outcomes of percutaneous vertebroplasty. / Kaufmann, Timothy J; Jensen, M. E.; Schweickert, P. A.; Marx, W. F.; Kallmes, David F.

In: American Journal of Neuroradiology, Vol. 22, No. 10, 2001, p. 1860-1863.

Research output: Contribution to journalArticle

Kaufmann, Timothy J ; Jensen, M. E. ; Schweickert, P. A. ; Marx, W. F. ; Kallmes, David F. / Age of fracture and clinical outcomes of percutaneous vertebroplasty. In: American Journal of Neuroradiology. 2001 ; Vol. 22, No. 10. pp. 1860-1863.
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