Advancing diagnostics to address antibacterial resistance: The diagnostics and devices committee of the Antibacterial Resistance Leadership Group

Ephraim L. Tsalik, Elizabeth Petzold, Barry N. Kreiswirth, Robert A. Bonomo, Ritu Banerjee, Ebbing Lautenbach, Scott R. Evans, Kimberly E. Hanson, Jeffrey D. Klausner, Robin Patel, Angie Caliendo, Charles Chiu, Romney Humphries, Melissa Miller, Chris Woods

Research output: Contribution to journalArticle

13 Scopus citations

Abstract

Diagnostics are a cornerstone of the practice of infectious diseases. However, various limitations frequently lead to unmet clinical needs. In most other domains, diagnostics focus on narrowly defined questions, provide readily interpretable answers, and use true gold standards for development. In contrast, infectious diseases diagnostics must contend with scores of potential pathogens, dozens of clinical syndromes, emerging pathogens, rapid evolution of existing pathogens and their associated resistance mechanisms, and the absence of gold standards in many situations. In spite of these challenges, the importance and value of diagnostics cannot be underestimated. Therefore, the Antibacterial Resistance Leadership Group has identified diagnostics as 1 of 4 major areas of emphasis. Herein, we provide an overview of that development, highlighting several examples where innovation in study design, content, and execution is advancing the field of infectious diseases diagnostics.

Original languageEnglish (US)
Pages (from-to)S41-S47
JournalClinical Infectious Diseases
Volume64
DOIs
StatePublished - 2017

Keywords

  • Antibacterial Resistance
  • Devices
  • Diagnostics

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Fingerprint Dive into the research topics of 'Advancing diagnostics to address antibacterial resistance: The diagnostics and devices committee of the Antibacterial Resistance Leadership Group'. Together they form a unique fingerprint.

  • Cite this

    Tsalik, E. L., Petzold, E., Kreiswirth, B. N., Bonomo, R. A., Banerjee, R., Lautenbach, E., Evans, S. R., Hanson, K. E., Klausner, J. D., Patel, R., Caliendo, A., Chiu, C., Humphries, R., Miller, M., & Woods, C. (2017). Advancing diagnostics to address antibacterial resistance: The diagnostics and devices committee of the Antibacterial Resistance Leadership Group. Clinical Infectious Diseases, 64, S41-S47. https://doi.org/10.1093/cid/ciw831