Advancing diagnostics to address antibacterial resistance: The diagnostics and devices committee of the Antibacterial Resistance Leadership Group

Ephraim L. Tsalik, Elizabeth Petzold, Barry N. Kreiswirth, Robert A. Bonomo, Ritu Banerjee, Ebbing Lautenbach, Scott R. Evans, Kimberly E. Hanson, Jeffrey D. Klausner, Robin Patel, Angie Caliendo, Charles Chiu, Romney Humphries, Melissa Miller, Chris Woods

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Diagnostics are a cornerstone of the practice of infectious diseases. However, various limitations frequently lead to unmet clinical needs. In most other domains, diagnostics focus on narrowly defined questions, provide readily interpretable answers, and use true gold standards for development. In contrast, infectious diseases diagnostics must contend with scores of potential pathogens, dozens of clinical syndromes, emerging pathogens, rapid evolution of existing pathogens and their associated resistance mechanisms, and the absence of gold standards in many situations. In spite of these challenges, the importance and value of diagnostics cannot be underestimated. Therefore, the Antibacterial Resistance Leadership Group has identified diagnostics as 1 of 4 major areas of emphasis. Herein, we provide an overview of that development, highlighting several examples where innovation in study design, content, and execution is advancing the field of infectious diseases diagnostics.

Original languageEnglish (US)
Pages (from-to)S41-S47
JournalClinical Infectious Diseases
Volume64
DOIs
StatePublished - 2017

Fingerprint

Communicable Diseases
Equipment and Supplies

Keywords

  • Antibacterial Resistance
  • Devices
  • Diagnostics

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Advancing diagnostics to address antibacterial resistance : The diagnostics and devices committee of the Antibacterial Resistance Leadership Group. / Tsalik, Ephraim L.; Petzold, Elizabeth; Kreiswirth, Barry N.; Bonomo, Robert A.; Banerjee, Ritu; Lautenbach, Ebbing; Evans, Scott R.; Hanson, Kimberly E.; Klausner, Jeffrey D.; Patel, Robin; Caliendo, Angie; Chiu, Charles; Humphries, Romney; Miller, Melissa; Woods, Chris.

In: Clinical Infectious Diseases, Vol. 64, 2017, p. S41-S47.

Research output: Contribution to journalArticle

Tsalik, EL, Petzold, E, Kreiswirth, BN, Bonomo, RA, Banerjee, R, Lautenbach, E, Evans, SR, Hanson, KE, Klausner, JD, Patel, R, Caliendo, A, Chiu, C, Humphries, R, Miller, M & Woods, C 2017, 'Advancing diagnostics to address antibacterial resistance: The diagnostics and devices committee of the Antibacterial Resistance Leadership Group', Clinical Infectious Diseases, vol. 64, pp. S41-S47. https://doi.org/10.1093/cid/ciw831
Tsalik, Ephraim L. ; Petzold, Elizabeth ; Kreiswirth, Barry N. ; Bonomo, Robert A. ; Banerjee, Ritu ; Lautenbach, Ebbing ; Evans, Scott R. ; Hanson, Kimberly E. ; Klausner, Jeffrey D. ; Patel, Robin ; Caliendo, Angie ; Chiu, Charles ; Humphries, Romney ; Miller, Melissa ; Woods, Chris. / Advancing diagnostics to address antibacterial resistance : The diagnostics and devices committee of the Antibacterial Resistance Leadership Group. In: Clinical Infectious Diseases. 2017 ; Vol. 64. pp. S41-S47.
@article{53f9aff93c8d4f5a8cbd5b4d5a3d5e54,
title = "Advancing diagnostics to address antibacterial resistance: The diagnostics and devices committee of the Antibacterial Resistance Leadership Group",
abstract = "Diagnostics are a cornerstone of the practice of infectious diseases. However, various limitations frequently lead to unmet clinical needs. In most other domains, diagnostics focus on narrowly defined questions, provide readily interpretable answers, and use true gold standards for development. In contrast, infectious diseases diagnostics must contend with scores of potential pathogens, dozens of clinical syndromes, emerging pathogens, rapid evolution of existing pathogens and their associated resistance mechanisms, and the absence of gold standards in many situations. In spite of these challenges, the importance and value of diagnostics cannot be underestimated. Therefore, the Antibacterial Resistance Leadership Group has identified diagnostics as 1 of 4 major areas of emphasis. Herein, we provide an overview of that development, highlighting several examples where innovation in study design, content, and execution is advancing the field of infectious diseases diagnostics.",
keywords = "Antibacterial Resistance, Devices, Diagnostics",
author = "Tsalik, {Ephraim L.} and Elizabeth Petzold and Kreiswirth, {Barry N.} and Bonomo, {Robert A.} and Ritu Banerjee and Ebbing Lautenbach and Evans, {Scott R.} and Hanson, {Kimberly E.} and Klausner, {Jeffrey D.} and Robin Patel and Angie Caliendo and Charles Chiu and Romney Humphries and Melissa Miller and Chris Woods",
year = "2017",
doi = "10.1093/cid/ciw831",
language = "English (US)",
volume = "64",
pages = "S41--S47",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",

}

TY - JOUR

T1 - Advancing diagnostics to address antibacterial resistance

T2 - The diagnostics and devices committee of the Antibacterial Resistance Leadership Group

AU - Tsalik, Ephraim L.

AU - Petzold, Elizabeth

AU - Kreiswirth, Barry N.

AU - Bonomo, Robert A.

AU - Banerjee, Ritu

AU - Lautenbach, Ebbing

AU - Evans, Scott R.

AU - Hanson, Kimberly E.

AU - Klausner, Jeffrey D.

AU - Patel, Robin

AU - Caliendo, Angie

AU - Chiu, Charles

AU - Humphries, Romney

AU - Miller, Melissa

AU - Woods, Chris

PY - 2017

Y1 - 2017

N2 - Diagnostics are a cornerstone of the practice of infectious diseases. However, various limitations frequently lead to unmet clinical needs. In most other domains, diagnostics focus on narrowly defined questions, provide readily interpretable answers, and use true gold standards for development. In contrast, infectious diseases diagnostics must contend with scores of potential pathogens, dozens of clinical syndromes, emerging pathogens, rapid evolution of existing pathogens and their associated resistance mechanisms, and the absence of gold standards in many situations. In spite of these challenges, the importance and value of diagnostics cannot be underestimated. Therefore, the Antibacterial Resistance Leadership Group has identified diagnostics as 1 of 4 major areas of emphasis. Herein, we provide an overview of that development, highlighting several examples where innovation in study design, content, and execution is advancing the field of infectious diseases diagnostics.

AB - Diagnostics are a cornerstone of the practice of infectious diseases. However, various limitations frequently lead to unmet clinical needs. In most other domains, diagnostics focus on narrowly defined questions, provide readily interpretable answers, and use true gold standards for development. In contrast, infectious diseases diagnostics must contend with scores of potential pathogens, dozens of clinical syndromes, emerging pathogens, rapid evolution of existing pathogens and their associated resistance mechanisms, and the absence of gold standards in many situations. In spite of these challenges, the importance and value of diagnostics cannot be underestimated. Therefore, the Antibacterial Resistance Leadership Group has identified diagnostics as 1 of 4 major areas of emphasis. Herein, we provide an overview of that development, highlighting several examples where innovation in study design, content, and execution is advancing the field of infectious diseases diagnostics.

KW - Antibacterial Resistance

KW - Devices

KW - Diagnostics

UR - http://www.scopus.com/inward/record.url?scp=85023188558&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85023188558&partnerID=8YFLogxK

U2 - 10.1093/cid/ciw831

DO - 10.1093/cid/ciw831

M3 - Article

C2 - 28350903

AN - SCOPUS:85023188558

VL - 64

SP - S41-S47

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

SN - 1058-4838

ER -