Abstract
Pharmacoresistant seizures occur in nearly one-third of people with epilepsy. Medial temporal lobe and lesional epilepsy are the most favorable surgically remediable epileptic syndromes. Successful surgery may render the patient seizure-free, reduce antiseizure drug(s) adverse effects, improve quality of life, and decrease mortality. Surgical management should not be considered a procedure of “last resort.” Despite the results of randomized controlled trials, surgery remains an underutilized treatment modality for patients with drug-resistant epilepsy (DRE). Important disparities affect patient referral and selection for surgical treatment. This article discusses the advances in surgical treatment of DRE in adults with focal seizures.
Original language | English (US) |
---|---|
Pages (from-to) | 181-196 |
Number of pages | 16 |
Journal | Neurologic clinics |
Volume | 39 |
Issue number | 1 |
DOIs | |
State | Published - Feb 2021 |
Keywords
- Drug-resistant
- Epilepsy
- Neuroimaging
- Surgical treatment
ASJC Scopus subject areas
- Clinical Neurology