Advances in the Surgical Management of Epilepsy: Drug-Resistant Focal Epilepsy in the Adult Patient

Research output: Contribution to journalReview articlepeer-review

Abstract

Pharmacoresistant seizures occur in nearly one-third of people with epilepsy. Medial temporal lobe and lesional epilepsy are the most favorable surgically remediable epileptic syndromes. Successful surgery may render the patient seizure-free, reduce antiseizure drug(s) adverse effects, improve quality of life, and decrease mortality. Surgical management should not be considered a procedure of “last resort.” Despite the results of randomized controlled trials, surgery remains an underutilized treatment modality for patients with drug-resistant epilepsy (DRE). Important disparities affect patient referral and selection for surgical treatment. This article discusses the advances in surgical treatment of DRE in adults with focal seizures.

Original languageEnglish (US)
Pages (from-to)181-196
Number of pages16
JournalNeurologic clinics
Volume39
Issue number1
DOIs
StatePublished - Feb 2021

Keywords

  • Drug-resistant
  • Epilepsy
  • Neuroimaging
  • Surgical treatment

ASJC Scopus subject areas

  • Clinical Neurology

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