Advances in neuroimaging of traumatic brain injury and posttraumatic stress disorder

Robert W. Van Boven, Greg S. Harrington, David B. Hackney, Andreas Ebel, Grant Gauger, J. Douglas Bremner, Mark D'Esposito, John A. Detre, E. Mark Haacke, Clifford R. Jack, William J. Jagust, Denis Le Bihan, Chester A. Mathis, Susanne Mueller, Pratik Mukherjee, Norbert Schuff, Anthony Chen, Michael W. Weiner

Research output: Contribution to journalReview articlepeer-review

78 Scopus citations


Improved diagnosis and treatment of traumatic brain injury (TBI) and posttraumatic stress disorder (PTSD) are needed for our military and veterans, their families, and society at large. Advances in brain imaging offer important biomarkers of structural, functional, and metabolic information concerning the brain. This article reviews the application of various imaging techniques to the clinical problems of TBI and PTSD. For TBI, we focus on findings and advances in neuroimaging that hold promise for better detection, characterization, and monitoring of objective brain changes in symptomatic patients with combat-related, closed-head brain injuries not readily apparent by standard computed tomography or conventional magnetic resonance imaging techniques.

Original languageEnglish (US)
Pages (from-to)717-756
Number of pages40
JournalJournal of Rehabilitation Research and Development
Issue number6
StatePublished - Jan 1 2009


  • Diagnosis
  • Diffusion tensor imaging
  • Neuroimaging
  • PTSD
  • Posttraumatic stress disorder
  • TBI
  • Traumatic brain injury
  • Veterans
  • fMRI

ASJC Scopus subject areas

  • Rehabilitation


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