Advances in metanephrine testing for the diagnosis of pheochromocytoma

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Pheochromocytoma is a lethal tumor of chromaffin cells of the adrenal medulla that produces episodes of hypertension with the symptoms of palpitations, severe headaches, and sweating. The diagnosis of pheochromocytoma is a challenging one; autopsy series suggest that many pheochromocytomas are not clinically suspected, and the undiagnosed tumor can be associated with morbid consequences. The testing of catecholamines, metanephrines, and Vanillylymandelic acid commonly is used for screening of pheochromocytoma. The diagnostic value of various biochemical tests, as reported in recent Mayo and National Institutes of Health studies, have been compared and discussed in detail. The recent developments in the methodologies of metanephrines testing also are presented.

Original languageEnglish (US)
Pages (from-to)85-103
Number of pages19
JournalClinics in Laboratory Medicine
Volume24
Issue number1
DOIs
StatePublished - Mar 2004

Fingerprint

Metanephrine
Pheochromocytoma
Tumors
Testing
Catecholamines
Screening
Health
Chromaffin Cells
Adrenal Medulla
Acids
Sweating
National Institutes of Health (U.S.)
Headache
Autopsy
Neoplasms
Hypertension

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Advances in metanephrine testing for the diagnosis of pheochromocytoma. / Singh, Ravinder Jit.

In: Clinics in Laboratory Medicine, Vol. 24, No. 1, 03.2004, p. 85-103.

Research output: Contribution to journalArticle

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