Advanced topics in evidence-based urologic oncology: Surrogate endpoints

Luke T. Lavallée, Victor M. Montori, Stephen E. Canfield, Rodney H. Breau

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

Clinical trials often report surrogate endpoint data. A surrogate endpoint is a biological marker or clinical sign that can be substituted for a patient-important outcome. Using surrogate endpoints correctly may facilitate and expedite clinical trials and may improve medical decisions. However, rigorous criteria must be met for an endpoint to be considered a valid surrogate. The purpose of this article is to review the topic of surrogate endpoints in the context of a urologic encounter.

Original languageEnglish (US)
Pages (from-to)447-453
Number of pages7
JournalUrologic Oncology: Seminars and Original Investigations
Volume29
Issue number4
DOIs
StatePublished - Jul 1 2011

Keywords

  • Biological Markers
  • Data Interpretation
  • Evidence-based medicine
  • Surrogate endpoints

ASJC Scopus subject areas

  • Oncology
  • Urology

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